DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3690 and CG3168

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	164/551 - (29%)
Similarity:	267/551 - (48%)	Gaps:	40/551 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PSESGDPKPHKTAEHQIGDP-PQKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMS 67
            |.:.|  |..|..:..:..| |.....|:||.||:..|:|.|:.:||......:.....:..:||
  Fly   110 PGKGG--KGGKGRKKSVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMS 172

  Fly    68 YILPSAECDLKLSLLDKGILNAITYAGMISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALS 132
            :|||||||||.|:...||.||:|.:.||:..|..||.:||..||:.:|||....:..|::..:.|
  Fly   173 FILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFS 237

  Fly   133 QSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPE 197
            |:....|:|::|.|..:.|...|:.:|..|...:..|..::..:...::...|.:..||.||:|.
  Fly   238 QTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPR 302

  Fly   198 TWNIQIWTLSLTSWQFFVAVTALPSLLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRK 262
            |........:..||:.|:.|.:|||.|...|.|:.|||||||:::|:...||..|:.::..|:::
  Fly   303 TIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKR 367

  Fly   263 PKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPTECVEVQDPENQDSKKSSLRSGFT-QLRPLF 326
            ..|.:.:..|  ||         ||.:            ::...|..:|.|.:.||.. ..|.||
  Fly   368 RPDEYMVYDL--EV---------DEKL------------LESNGNVKNKYSRMISGMVDHSRALF 409

  Fly   327 TKPYLGLSLWVYLLNFCVLLGQNTMRLWLPQLFASINEYENLMSGESQSTSICNILEYSVNRTQS 391
            ..|.|..::....:||...:|...:.:|.|:||....|||...  ..||..:|.:.:|.||..:.
  Fly   410 KSPILRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAF--PDQSAGVCAVTDYVVNLAKE 472

  Fly   392 QLEAVTRNDPTVECHVIITPSTYTNNLIVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSI 456
            |     .|:.|  |...|..|.:..:||...:...|.:||...::::|.|..:.:|.:.|..||.
  Fly   473 Q-----SNNGT--CSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSA 530

  Fly   457 GMYWSSSAASTVALASLFVTMGSISATSVI--SASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIF 519
            .||:..|:...:.::::|  .|:|||.:..  .....:|||.||...|::.|:..|||.::|||.
  Fly   531 LMYFVRSSVQNLVVSAIF--SGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIV 593

  Fly   520 FPALMGLGCVPPFLMISAFMLAGCFMAAFLP 550
            ...|:...|..|..::|..::.|..|...||
  Fly   594 IAQLLDNYCPSPTFIVSGLLIGGGLMCLLLP 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	150/509 (29%)
		MFS	49..>195	CDD:119392	46/145 (32%)
		MFS	419..>550	CDD:119392	37/132 (28%)
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	143/482 (30%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	147/502 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I3080
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8715
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.070