DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3690 and Svop

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_599231.3	Gene:	Svop / 171442	RGDID:	620277	Length:	548	Species:	Rattus norvegicus

Alignment Length:	540	Identity:	112/540 - (20%)
Similarity:	211/540 - (39%)	Gaps:	115/540 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAECDLKLSLLDKGILNAITYAGMIS 97
            |.|::|.|||.|...|.|....|.|....|...:|.:.|...|:.:|......:|.::.:.||:|
  Rat    71 EDAVEAIGFGRFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMS 135

  Fly    98 SAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSG-PFAVLMTYLT 161
            |:.|||.::|..||:..|.:.........:..|.:.....::|.:.|.||.:.| |.:|  |...
  Rat   136 SSTLWGNISDQYGRKTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSV--TLYA 198

  Fly   162 ELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLLSF 226
            |....|.|.:.::::.:.::|.|:....||:.::|.           ..|::.:.::|.|.|:..
  Rat   199 EFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMPS-----------LGWRWLLLLSAAPLLVFA 252

  Fly   227 VLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETIPT 291
            ||.|:.|||.::.:..|...:|:...|                                  .|.|
  Rat   253 VLCFWLPESARYDVLSGNQEKAIATLK----------------------------------RIAT 283

  Fly   292 ELKLPTECVEVQDPENQDSKKSSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVLLGQNTMRLWLP 356
            |...|....::.....:|..|         :|.|||..:...:|.::.:.|........:.|...
  Rat   284 ENGAPMPLGKLIISRQEDRGK---------MRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTT 339

  Fly   357 QLFASINEYENLMSGESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHV---IITPSTYTNNL 418
            :||              |:..:|:|        .|:.:||     ..:|.:   .::...|.:.|
  Rat   340 ELF--------------QAGDVCSI--------SSRKKAV-----EAKCSLACEYLSKEDYMDLL 377

  Fly   419 IVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVALASLFVT----MGS 479
            ....:.|...::..::::.:|.|..|....:|.:.||:.::  ......|....||:.    .|.
  Rat   378 WTTLSEFPGVLVTLWVIDRLGRKKTMALCFVIFSLCSLLLF--ICIGRNVLTLLLFIARAFISGG 440

  Fly   480 ISATSVISASVSLFPTSLRTMIVSLEMMFGRLGSLL----------GNIFFPALMGLGCVPPFLM 534
            ..|..|.:..|  :||:.|.:.:.......|:|:|:          .:::....:..||    .:
  Rat   441 FQAAYVYTPEV--YPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGC----CL 499

  Fly   535 ISAFMLAGCFMAAFLPLKNK 554
            ::|  ||.|    |||::.|
  Rat   500 LAA--LASC----FLPIETK 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	103/524 (20%)
		MFS	49..>195	CDD:119392	36/146 (25%)
		MFS	419..>550	CDD:119392	27/144 (19%)
Svop	NP_599231.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	523..548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010