Protein Alignment CG3690 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_001284764.1
• Gene: CG3690 / 31047
• FlyBaseID: FBgn0040350
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 113/476 - (23%)
• Similarity: 172/476 - (36%)
• Gaps: 152/476 - (31%)

  Fly    94 GMISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFAVLMT 158
            |.:...|:.|...|..|||.:.:......|......||:.|...|:|.:.|.|..::|  |:|..
Human    29 GWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAASFPTLLVLRLLHGGTLAG--ALLAL 91

  Fly   159 YLT--ELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALP 221
            ||.  ||....||....|..|:...:.||.|||||.|       :|.|.|          :..|.
Human    92 YLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAAL-------VQDWRL----------LQGLG 139

  Fly   222 SLLSFVLFFF------FPESPKFLMSKG---RNREALDAFKFMYHLNSRKPKDSFPIKLLANEVI 277
            :|:|.:|..|      |||||.:|::.|   |.|:.|..|.   ..:...|.||
Human   140 ALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFA---EASGVGPGDS----------- 190

  Fly   278 VPVKKHAKDETIPTELKLPTECVEVQDPENQDSKKSSLRSGFTQLRPLFTKPYLGLSLWVYLLNF 342
                 ..::.::.|||.:    :..:.|:                 |.:..| |||
Human   191 -----SLEENSLATELTM----LSARSPQ-----------------PRYHSP-LGL--------- 219

  Fly   343 CVLLGQNTMRLWLPQLFASINEYENLMSGESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHV 407
                 ..|...|...|   |..:.:|:.|.         :..|..|:.:         |.|
Human   220 -----LRTRVTWRNGL---ILGFSSLVGGG---------IRASFRRSLA---------PQV---- 254

  Fly   408 IITPSTYTNNLIVAG---AGFVAYMLAGFL-----VNLVGVKLIMTSGLLIAAGCSIGMYWSSSA 464
               |:.|....:.||   |..|..:|....     |.|:|..:...:.||:.||......|
Human   255 ---PTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAGAQYLPGW---- 312

  Fly   465 ASTVALASLFVTMGSISATSVISASVSL-----FPTSLR----TMIVS----------LEMMFGR 510
              ||    ||:::..:.|:..:||..||     |||.:|    .:::.          |:.:.||
Human   313 --TV----LFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGR 371

  Fly   511 LGSLLGNIFFP--ALMGLGCV 529
            .|..|..:.|.  |::.|.||
Human   372 QGFFLQQVVFASLAVLALLCV 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	113/476 (24%)
		MFS	49..>195	CDD:119392	34/102 (33%)
		MFS	419..>550	CDD:119392	36/140 (26%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	109/465 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153581
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930