Protein Alignment CG3690 and Sv2b

DIOPT Version :9

• Sequence 1: NP_001284764.1
• Gene: CG3690 / 31047
• FlyBaseID: FBgn0040350
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_476555.1
• Gene: Sv2b / 117556
• RGDID: 619716
• Length: 683
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 140/616 - (22%)
• Similarity: 250/616 - (40%)
• Gaps: 118/616 - (19%)

  Fly    25 QKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAECDLKLSLLDKGILNA 89
            :::.|..:|..||..|.|.|...|....|.|.|....|...:|:.|||||.|:.||...||:|..
  Rat    88 EEQLAHQYETIIDECGHGRFQWTLFFVLVLALMADGVEVFVVSFALPSAEKDMCLSSSKKGMLGL 152

  Fly    90 ITYAGMISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFA 154
            |.|.||::.|.:.|.|||..||:.:|.:..|.:.......:..|.....:..:.:.|..:.|...
  Rat   153 IVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLP 217

  Fly   155 VLMTYLTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPE-TWNIQIWT-LSLTSWQFFVAV 217
            ::..|.:|...|:.|...:..:||.:....:....:|..|:|. .|...:.| ....||:.||.|
  Rat   218 IVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIV 282

  Fly   218 TALPSLLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSR---KPKDSFPIKLLANEVIVP 279
            .|||:.:|.|...|.||||:||:..|::.||....|.::..|.|   .|:..|.:
  Rat   283 CALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTV---------- 337

  Fly   280 VKKHAKDETIPTELKLPTECVEVQDPENQDSKKSSLRSGFTQLRPLFTK-----------PYLGL 333
              .|.|   .|.::   .|.:|:     |.|..:..:....:...:|.:           ||...
  Rat   338 --SHIK---TPKQM---DEFIEI-----QSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMN 389

  Fly   334 SLWVYLLNFCVLLGQNTMRLWLPQL--FASINEYENLMS---GESQSTSICNI-LEYSVNR---- 388
            :|.:.::.|.:.|....:.:|.|.:  :....||::.|.   ||....:..|. :|..:::
  Rat   390 TLILAVVWFTMALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKL 454

  Fly   389 --------------------TQSQLEAVTRNDP-----TVE------------------------ 404
                                .:...|.||..|.     |:|
  Rat   455 VNDKFIKMYFKHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFIDCRFINSTF 519

  Fly   405 ------CHVIITPSTYTNNLIVAGAGFVAYM-------LAGFLVNLVGVKLIMTSGLLIAAGCSI 456
                  ||:.....   |:.::....|:..:       ::..|::.:|...::...:||:|.|..
  Rat   520 LEQKEGCHMDFEED---NDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCF 581

  Fly   457 GMYWSSSAASTVALASLF--VTMGSISATSVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIF 519
            .:::.:|.::.:....||  .::.:.:|..||  :|.|:||:.|.....:.....:||::|||..
  Rat   582 FLFFGNSESAMIGWQCLFCGTSIAAWNALDVI--TVELYPTNQRATAFGILNGLCKLGAILGNTI 644

  Fly   520 FPALMGLGCVPPFLMISAFMLAGCFMAAFLP 550
            |.:.:|:..|.|.|:.:|.::.|..:|..||
  Rat   645 FASFVGITKVVPILLAAASLVGGGLVALRLP 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	133/596 (22%)
		MFS	49..>195	CDD:119392	39/145 (27%)
		MFS	419..>550	CDD:119392	31/139 (22%)
Sv2b	NP_476555.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..72
		synapt_SV2	8..683	CDD:130366	140/616 (23%)
		MFS	112..>305	CDD:119392	59/192 (31%)
		MFS	534..>675	CDD:119392	32/142 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8952
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920