DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3699 and MGC147226

DIOPT Version :9

Sequence 1:	NP_569875.2	Gene:	CG3699 / 31046	FlyBaseID:	FBgn0040349	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_012816817.1	Gene:	MGC147226 / 780086	XenbaseID:	XB-GENE-5822220	Length:	521	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	85/253 - (33%)
Similarity:	132/253 - (52%)	Gaps:	14/253 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEAT--KKSLKGTQAEIVVADVTK 63
            |.|..:|..|||...|||.|.|..|...||.:|:|...:...||.  :..:||.::..:.||::|
Frog   272 MRLDGRVAYVTGGGQGIGRAFAHALGEAGAKVAVVDLMLEKAEAVAFELQVKGIKSVAIAADISK 336

  Fly    64 DADA--IVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLTKAVLPHLL- 125
            :.|.  ||...:..:||||:..|||||.......|..:||:|...:.||||:.:..:|....:|
Frog   337 EEDVKRIVDTIVTNWGRIDIACNNAGINMNSASEDTTLEEWDKTFSVNLRGLFMCCQAAGRVMLS 401

  Fly   126 KTKGAVVNVSSCAGI---RPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNPGFVVTNIH 187
            :..|.::|.:|.|.:   .| ...|:|..|||.:.:.|:.:..|...:|||||.::||.|.|.:
Frog   402 QGYGKIINTASMASLIVPHP-QKQLAYNTSKAGVVKLTQTLGTEWIDRGVRVNCISPGIVDTPL- 464

  Fly   188 RNIGIVDEEYNGMLQRAINSHPMGRVGDVTEVAEAVAFLASSKASFTTGALFPIDGGK 245
                |..:....::||.:|..|.||:..||::...|.||||..:.:.||....|:||:
Frog   465 ----IHSDALKPLVQRWLNDIPAGRLAQVTDLQAGVVFLASEASDYMTGHNLVIEGGQ 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3699	NP_569875.2	fabG	1..244	CDD:235546	83/250 (33%)
CG3699	NP_569875.2	NADB_Rossmann	3..248	CDD:304358	84/251 (33%)
MGC147226	XP_012816817.1	AdoMet_MTases	78..241	CDD:388410
MGC147226	XP_012816817.1	NADB_Rossmann	269..518	CDD:389744	84/251 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910