DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3699 and PECR

DIOPT Version :9

Sequence 1:	NP_569875.2	Gene:	CG3699 / 31046	FlyBaseID:	FBgn0040349	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_060911.2	Gene:	PECR / 55825	HGNCID:	18281	Length:	303	Species:	Homo sapiens

Alignment Length:	266	Identity:	86/266 - (32%)
Similarity:	128/266 - (48%)	Gaps:	39/266 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGT-----QAEIVVADVT 62
            |..:|.||||.::|||.||.:.|...|:.:.:..|.:..|::....|:..     ||.::.....
Human    16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80

  Fly    63 ----KDADAIVQQTLAKFGRIDVLVNNAG---------ILGKGGLIDLDIEEFDAVLNTNLRGVI 114
                ::.:.:|:.||..||:|:.||||.|         |..||         :.|||.|||.|..
Human    81 IRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKG---------WHAVLETNLTGTF 136

  Fly   115 LLTKAVLPHLLKTK-GAVVN--VSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNS 176
            .:.|||....:|.. |::||  |.:.||   |..|:..|.::|.:...||.:|||.|..|:|:|.
Human   137 YMCKAVYSSWMKEHGGSIVNIIVPTKAG---FPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198

  Fly   177 VNPGFVVTNIH-RNIGIVDEE-YNGMLQRAINSHPMGRVGDVTEVAEAVAFLASSKASFTTGALF 239
            |.||.:.:... .|.|...:. :.|..|:.    |..|:|...||:..|.||.|..|||.||...
Human   199 VAPGVIYSQTAVENYGSWGQSFFEGSFQKI----PAKRIGVPEEVSSVVCFLLSPAASFITGQSV 259

  Fly   240 PIDGGK 245
            .:|||:
Human   260 DVDGGR 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3699	NP_569875.2	fabG	1..244	CDD:235546	84/263 (32%)
CG3699	NP_569875.2	NADB_Rossmann	3..248	CDD:304358	86/266 (32%)
PECR	NP_060911.2	TER_DECR_SDR_a	16..267	CDD:187627	86/266 (32%)
PECR	NP_060911.2	Microbody targeting signal	301..303
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810