Protein Alignment CG3699 and RDH8

DIOPT Version :10

• Sequence 1: NP_569875.2
• Gene: CG3699 / 31046
• FlyBaseID: FBgn0040349
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_056540.3
• Gene: RDH8 / 50700
• HGNCID: 14423
• Length: 311
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 65/209 - (31%)
• Similarity: 102/209 - (48%)
• Gaps: 21/209 - (10%)

  Fly     1 MSLSNKVVIVTGASSGIGAAIAQVLAREG-------ATLALVGRNVANLEATKKSLKGTQAEIVV 58
            |:.:.:.|:::|.|||||..:|..||.:.       ||:..:|:. ..|||......|....:..
Human     1 MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKK-ETLEAAAGEALGQTLTVAQ 64

  Fly    59 ADVTKDADAIVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLTKAVLPH 123
            .||..| :::.|......|.:||||||||:...|.|..|.:.....|.:||..|.:.|.|||||.
Human    65 LDVCSD-ESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPG 128

  Fly   124 LLKTK-GAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNPGFVVTNIH 187
            :.:.: |.:|.:||..|::.......|..||.||:.|.:.:|:::....:.::.|.||.|||
Human   129 MKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVT--- 190

  Fly   188 RNIGIVDEEYNGML 201
                    |:.|.|
Human   191 --------EFEGKL 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3699	NP_569875.2	Rossmann-fold NAD(P)(+)-binding proteins	3..248	CDD:473865	64/207 (31%)
RDH8	NP_056540.3	type1_17beta-HSD-like_SDR_c	6..262	CDD:187666	64/204 (31%)