DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3699 and hsdl2

DIOPT Version :9

Sequence 1:	NP_569875.2	Gene:	CG3699 / 31046	FlyBaseID:	FBgn0040349	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001008673.1	Gene:	hsdl2 / 493329	XenbaseID:	XB-GENE-5753362	Length:	417	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	73/276 - (26%)
Similarity:	118/276 - (42%)	Gaps:	74/276 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGT----QAEI------- 56
            |:...:.:||||.|||.|||...||:||.:.:..:..   ||..| |.||    .:||
Frog     8 LAGCTLFITGASRGIGKAIALKAARDGANVVIAAKTA---EAHPK-LPGTIYTAASEIEAAGGKA 68

  Fly    57 --VVADVTKD--ADAIVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLT 117
              .:.||..:  ..|.|::.:..||.||:|||||..:.....::..:::.|.::..|.||..|.:
Frog    69 LPCIVDVRDENQISAAVEKAVDTFGGIDILVNNASAISLTNTLETPMKKVDLMMGINTRGTYLTS 133

  Fly   118 KAVLPHLLKTKGA-VVNVSSCAGIRP--FAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNP 179
            |..:|:|.|:|.| ::|:|....:.|  |....:|.::|..:    .:.||.|:
Frog   134 KICIPYLKKSKVAHILNLSPPLNLNPIWFKNHCAYTIAKYGM----SMCALGMS----------- 183

  Fly   180 GFVVTNIHRNIGIVDEEYNGML-------QRAINSHPMGRVG-----------DVTEVAEAVAFL 226
                           |||.|.:       :.||::..|..:|           |:  :|:|...:
Frog   184 ---------------EEYKGEIAVNALWPKTAIHTAAMDMLGGSGVDKQCRTPDI--MADAAYAI 231

  Fly   227 ASSKASFTTGALFPID 242
            .|....||..  |.||
Frog   232 LSKPKDFTGN--FVID 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3699	NP_569875.2	fabG	1..244	CDD:235546	73/276 (26%)
CG3699	NP_569875.2	NADB_Rossmann	3..248	CDD:304358	73/276 (26%)
hsdl2	NP_001008673.1	HSDL2_SDR_c	8..248	CDD:187663	73/276 (26%)
hsdl2	NP_001008673.1	SCP2	313..410	CDD:376720
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910