DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3703 and plx

DIOPT Version :9

Sequence 1:	NP_569874.1	Gene:	CG3703 / 31045	FlyBaseID:	FBgn0040348	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	NP_001163511.1	Gene:	plx / 40704	FlyBaseID:	FBgn0261261	Length:	1572	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	93/463 - (20%)
Similarity:	145/463 - (31%)	Gaps:	157/463 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 HGPDSQLI----QQLKS---QLTELEQIAYEAGEP--------GILPQHVLLEKQKF--ILDELR 215
            |.|.::.|    .||||   |.:....:|...|..        |:  :|.|.....:  :.....
  Fly    76 HKPQAKSIGNGFLQLKSSAGQTSSSSAVASSMGGAASSSLTGNGL--RHTLTASTSYGSLSSSAA 138

  Fly   216 AKLNLQVEQHELPALSTEQLRHQVDNAIGEFVGPLKMKEQLVAQLKTQITDLERFIAFLQCDAIE 280
            ....||::|      |.|....|..|.: ||.||:.....|:...|..:..:..|    :|:|:|
  Fly   139 CAYQLQLQQ------SAEASAEQPQNFM-EFQGPITGLVYLLKDPKDPLLHIYLF----ECEAVE 192

  Fly   281 -----------------GSVGDRLKLL-----------SGAYNSYAAKQTARSSQASYVATNAPA 317
                             ||||...:.|           :||.|...| ..|.:.:.|....||..
  Fly   193 EMAELMHQMRDPAHTLGGSVGSIPQTLIGGGGGSHGNSNGALNGIHA-TPATNLKMSEAMRNAQH 256

  Fly   318 TTATTPPSSGLGAHSSGESLHSKAHGLLDKASVL-----------MQMFAS-----THL------ 360
            .|:..|.||.:.|..      |..|||...:..:           :.:.|.     ||.
  Fly   257 DTSPNPVSSKMKASK------SYTHGLSSSSGTVNIPTSTSAQSNLSLLADISPNHTHFFEVMYV 315

  Fly   361 -------------------------------------------------VKP----RTHD-EFQQ 371
                                                             .||    ::|| :.:.
  Fly   316 GKIRVSQKRVPNTFIDDALPKFKAYDAQRLRLLQNRKMSLSSEGGVGIEAKPSSSLKSHDLKEED 380

  Fly   372 NSLKKTHKGNHWG-DLRA----QLEVDIQEVAALAATLSCDREKLANIKRALRKQQQQAE--STE 429
            ...::.|||:... |.:|    ||::...|..|....|..::|..:..||.|.:.|.|.|  ..|
  Fly   381 EEEQEQHKGHDDSQDSQAKPLVQLQLTGAEEGAAPRPLEDNKENKSPEKRPLLRGQSQIELGHKE 445

  Fly   430 FSDTGNPVINSQNGALTLPPRCRRAVPTGHELAPYASG---GAISSDSDEDISYSNFEWEKESKS 491
            .||...|:  :.|..|..|.......||    .|...|   |..|:.:.....:.|:..:...|.
  Fly   446 HSDGSQPL--AANSQLEAPNVIVNKQPT----PPRDQGVGTGTASASAGPSQLHPNYAMDNIPKQ 504

  Fly   492 RRTTHARG 499
            |..:.::|
  Fly   505 RDRSASQG 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3703	NP_569874.1	RUN	516..703	CDD:280855
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967	40/218 (18%)
		DUF3350	835..880	CDD:288663
		TBC	933..1152	CDD:214540
		RILP-like	<1176..1267	CDD:304877
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100