DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3703 and GAPcenA

DIOPT Version :9

Sequence 1:	NP_569874.1	Gene:	CG3703 / 31045	FlyBaseID:	FBgn0040348	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	NP_001097549.1	Gene:	GAPcenA / 38945	FlyBaseID:	FBgn0035879	Length:	1194	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	52/293 - (17%)
Similarity:	104/293 - (35%)	Gaps:	65/293 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EAQETKDSCSTIEGQLPAGPVRA-EDEEEEVEVEQEQQELLSERWSPLGANYDDANSASSGV--- 67
            |.::.:.....:..||.:...|| |.|::...:.||.::::..:       ..|.|:.|..:
  Fly   930 ERRKMQAEIDALNKQLTSAKERAVEKEKKHTGIIQEYKQIIQRQ-------EQDMNTLSETLGKV 987

  Fly    68 --------DC--ELEPGLEKSEARRGSTGSELARLRSIEEEQELLTSSLLALTSHFAHVQLRVRQ 122
                    ||  :::.|.:.:::..|....:...:|:..|........|.|.:.....::|.:.|
  Fly   988 MHMVSNCQDCQQQIDAGNDNAKSDDGKNRGQTDAMRNANEHPLGPLDPLNAASQRIRELELELAQ 1052

  Fly   123 I----VEAPAEERD---QLLRDLEDF-------------AFQGIPDAVQSKESHPDKPASDGEKD 167
            .    |||..:.:|   ||...|.:.             .|..:.:.|.::..|.|..:.
  Fly  1053 AKLAQVEAECKNQDLNHQLSNTLSELQTNRNSWQPWLSKTFNSLQEKVTTRGGHRDNGSG----- 1112

  Fly   168 HGPDSQLIQQLKSQLTELEQIAYEAGEPGILPQHVLLEKQKFILDELRAKLNLQVEQHELPA-LS 231
             ||.......:....|.|.:.:..:|..         |.:.|....:..       ..:||: ..
  Fly  1113 -GPMPSFQSYMGQAPTTLSEASSPSGNQ---------EYKTFAFASVGG-------SPKLPSKFQ 1160

  Fly   232 TEQLRHQVDNAIGEFVGPLKMKEQLVAQLKTQI 264
            ..:||:.:| ::...|.||...:.|...||.|:
  Fly  1161 ATKLRNSID-SLRNIVVPLDTGKTLAENLKQQL 1192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3703	NP_569874.1	RUN	516..703	CDD:280855
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256
		TBC	650..858	CDD:214540
		Phage_Gp23	<914..991	CDD:287621	12/67 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100