DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3703 and Tbc1d15-17

DIOPT Version :9

Sequence 1:	NP_569874.1	Gene:	CG3703 / 31045	FlyBaseID:	FBgn0040348	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	59/314 - (18%)
Similarity:	111/314 - (35%)	Gaps:	54/314 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EMKMAEAQETKDSCSTIEGQLPAGPVRAEDEEEEVEVEQ-EQQELLSERWSP------LGANYDD 59
            :..:.|..||..|...:...|.....:.:....|:::.| :..:|..|.|.|      || |..|
  Fly   192 DQHLIENAETSRSGGEVYAILTTENQKLKKTFAELDIGQIKASQLPRESWLPNKLAGILG-NIPD 255

  Fly    60 ANSASSGVDCELEPGLEKSEARRGSTGSELARLRSIEEEQEL-LTSSLLALTSHFAHVQLRVRQI 123
                      .::|..::|...|........|..|.:..|.: |:.|..:..|  ::.|.|....
  Fly   256 ----------YVQPPFQRSPKSRPGVLISGDRQTSPDNYQIIGLSGSTNSACS--SNGQSRGGSA 308

  Fly   124 VEAPAEERDQLLRDLEDFAFQGIPDAVQSKESHPDKPASDGEKDHGPDSQLIQQLKSQLTELEQI 188
            .::||:...:.|...::.....:||..:.:..|| ...:...:...||.::     |....::::
  Fly   309 EKSPADSELETLNAQDEKIVNNLPDRQRVERGHP-LTETQWLEFQTPDGRI-----SDSARIKEL 367

  Fly   189 AYEAGEPGILPQHVLLEKQKFIL----------DELRAKLNLQVEQHELPALSTEQLRHQVDNAI 243
            .:..|    :.|.:..|..||:|          :.:..:....:|.:.:.|........|..|
  Fly   368 IFRGG----VVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEAN-- 426

  Fly   244 GEFVGPLKMKEQLVAQLKTQITDLERFIAFLQCDAIEGSVGDRLKLLSGAYNSY 297
              |.|..:.|.|:...:|.....|:.|         .|.....|.||.|...:|
  Fly   427 --FCGYRERKCQIEKDVKRTDRSLQFF---------AGEDNPNLTLLQGILMTY 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3703	NP_569874.1	RUN	516..703	CDD:280855
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	23/118 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100