Protein Alignment CG3703 and SGSM3

DIOPT Version :9

• Sequence 1: NP_569874.1
• Gene: CG3703 / 31045
• FlyBaseID: FBgn0040348
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: XP_024307987.1
• Gene: SGSM3 / 27352
• HGNCID: 25228
• Length: 820
• Species: Homo sapiens
• Alignment Length: 821
• Identity: 152/821 - (18%)
• Similarity: 260/821 - (31%)
• Gaps: 294/821 - (35%)

  Fly    27 VRAEDEEEEVEVEQEQQELLSERWSPLGANYDDANSASSGVD---------CELEPGLEKSEARR 82
            |:....:|.:..:|.:::||  |..|..|.:  |:..|.||.         ..|.|.:...:
Human   145 VKNSSNDETIAAKQIEKDLL--RTMPSNACF--ASMGSIGVPRLRRVLRALAWLYPEIGYCQ--- 202

  Fly    83 GSTGSELA-RLRSIEEE----------QELLTSSLLALTSHFAHVQLRV-RQIVEAPAEERDQLL 135
             .||...| .|..:|||          ::||.:|..:.|........|| |.::.......|:||
Human   203 -GTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLL 266

  Fly   136 RD---------LEDF--AFQGIPDAVQSKESHPDKPASDGEKDHGPDSQLIQQLKSQLTELEQIA 189
            ::         |..|  ||..:.|                             :|..|...:...
Human   267 QEHDIELSLITLHWFLTAFASVVD-----------------------------IKLLLRIWDLFF 302

  Fly   190 YEAGEPGILPQHVL----LEKQKFILDELRAKLNLQVEQHELPALSTEQLRHQVDNAIGEFVGPL 250
            ||...  :|.|..|    |::::.|..|..|                     .:.|.:.:....:
Human   303 YEGSR--VLFQLTLGMLHLKEEELIQSENSA---------------------SIFNTLSDIPSQM 344

  Fly   251 KMKEQLVA---QLKTQITDL------ERFIAFLQCDAIEGSVGDRLKLLSGAYNSYAAKQTARSS 306
            :..|.|:.   :|...:||:      .:.:|:|        :.|:.:||.....:..::...|.:
Human   345 EDAELLLGVAMRLAGSLTDVAVETQRRKHLAYL--------IADQGQLLGAGTLTNLSQVVRRRT 401

  Fly   307 QASYVATNAPATTATTPPSSGLGAHSSGESLHSKAHGLLDKASVLMQMFASTHLVKPRTHDEFQQ 371
            |     ......||.....|...|...|.:      |:...|.|.:::       .||
Human   402 Q-----RRKSTITALLFGESSASARQCGHA------GVCPHAHVDVEL-------PPR------- 441

  Fly   372 NSLKKTHKG-----NHWGDLRAQLEVDIQEVAALAATLSCDREKLANIKRALRKQQQQAESTEFS 431
                    |     .|.|.|....|.|::   ||.|......|.:|:::.|:.:..:..:.|:..
Human   442 --------GPGVGCGHHGSLGLLGEDDLE---ALKAKNIKQTELVADLREAILRVARHFQCTDPK 495

  Fly   432 DTGNPVINSQ------NGALTLPPRCRRAVPTGHELAPYASGGAISSDSDEDISYS--------- 481
            :..  |::.|      |.|||.|...........||.|..|..:...|.:..::.|
Human   496 NCS--VVSRQLPGLLPNTALTPPTPLVGLCSLWQELTPDYSMESHQRDHENYVACSRSHRRRAKA 558

  Fly   482 --NFEWEKESK------------SRRTTHA-----------------------------RGDSIA 503
              :||...:.:            |::..|.                             .||...
Human   559 LLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSV 623

  Fly   504 TIGRELTTVVRKNFARTLQQLIQHGLRIPAESAASSLMVPFMRCLHPGPPVVPPAVGGDSQFLGL 568
            |.|  :|.:||......|:.|.:|||:.|      ||                           |
Human   624 TEG--VTDLVRGTLCPALKALFEHGLKKP------SL---------------------------L 653

  Fly   569 GRAMHAW-------------ELVLAYYRLKHGEEYNNTPARKLSQSFQLDIVDAQAVTAKQSLLS 620
            |.|.|.|             :....|.||            .|.::|:|| .|.:.:|.::.|..
Human   654 GGACHPWLFIEEAAGREVERDFASVYSRL------------VLCKTFRLD-EDGKVLTPEELLYR 705

  Fly   621 AVGMILAMHRPYKRSNNAHFKAFVCAGLNSHLLVEWLNLILSCHELVDTYYSADSYVARTGFRDS 685
            ||..:...|.......:...::.:|.|||..:|..||.::.|....|:.:|...|::...|:...
Human   706 AVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQI 770

  Fly   686 LRSIDALSRF------DFDLPV-------------DLAIRH 707
            ...:..|..|      |::||.             |:.::|
Human   771 KCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKH 811

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3703	NP_569874.1	RUN	516..703	CDD:280855	43/218 (20%)
SGSM3	XP_024307987.1	TBC	114..325	CDD:214540	44/218 (20%)
		SH3_SGSM3	555..607	CDD:212747	4/51 (8%)
		RUN	634..785	CDD:308412	40/196 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910