Protein Alignment CG3703 and rund-1

DIOPT Version :9

• Sequence 1: NP_569874.1
• Gene: CG3703 / 31045
• FlyBaseID: FBgn0040348
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_508136.2
• Gene: rund-1 / 180416
• WormBaseID: WBGene00020572
• Length: 549
• Species: Caenorhabditis elegans
• Alignment Length: 705
• Identity: 217/705 - (30%)
• Similarity: 319/705 - (45%)
• Gaps: 195/705 - (27%)

  Fly    39 EQEQQELLSERWSPLGANY-----DDANSASSGVD-CELEPGLEKSEARRGSTGS-------ELA 90
            |.|..:||.|    ||.:.     :|:.....|:| .:.....|...||..|:.|       :..
 Worm     4 ELEASDLLVE----LGQSLKKRASEDSKEIVDGLDFYDTMSETEWKSARLSSSHSDDIGSLNDAL 64

  Fly    91 RLRSIEEEQELLTSSLLALTSHFAHVQLRVRQIVEAPAEERDQLLRDLEDFAFQGIPD--AVQSK 153
            |::.:|||||.|.:||.:|:||||.||.|::|:.||...:|.:||.||:.|||:|..|  .:|..
 Worm    65 RVQQLEEEQERLNNSLFSLSSHFAQVQFRIKQMNEADPSDRLKLLSDLQKFAFKGCTDMNELQRL 129

  Fly   154 ESHPDKPASDGEKDHGPDSQLIQQLKSQLTELEQIAYEAGEPGILPQHVLLEKQKFILDELRAKL 218
            .|..:......:|.:....:|::||:.|:.:||:.|||.|| |.||...:|:|||.:||:||.|:
 Worm   130 RSESESGNDVLDKQNERQKELLKQLREQVEDLERTAYENGE-GELPSTDILKKQKAVLDKLREKI 193

  Fly   219 NLQVEQHELPALSTEQLRHQVDNAIGEFVGPLKMKEQLVAQLKTQITDLERFIAFLQCDAIEGSV 283
            .|.:   ::..::..:::.|||:|:.:.|.|.|.|.|||.||:|||||||||:.|||
 Worm   194 ELNL---DIDKMNQTEIQRQVDDALKQLVNPFKEKGQLVDQLQTQITDLERFVNFLQ-------- 247

  Fly   284 GDRLKLLSGAYNSYAAKQTARSSQASYVATNAPATTATTPPSSGLGAHSSGESLHSKAHGLLDKA 348
                            |:.|.:|.    .|....:..:||.|   ||.|...|..|...|
 Worm   248 ----------------KENAENSN----QTTPVRSMGSTPLS---GAKSKNGSFLSGIIG----- 284

  Fly   349 SVLMQMFASTHLVKPRTHDEFQQNSLKKTHKGNHWGDLRA--QLEVD-IQEVAALAATLSCDREK 410
                   .||        ..||:|.||.|.||||:||.||  ||.|| .|:|......|:.|
 Worm   285 -------CST--------GRFQKNQLKNTLKGNHYGDERAHVQLAVDATQQVLEKYTLLTFD--- 331

  Fly   411 LANIKRALRKQQQQAESTEFSDTGNPVINSQNGALTLPPRCRRAVPTGHELAPYASGGAISSDSD 475
                                        ::..|.|
 Worm   332 ----------------------------SATKGQL------------------------------ 338

  Fly   476 EDISYSNFEWEKESKSRRTTHARGDSIATIGRELTTVVRKNFARTLQQLIQHGL--------RIP 532
            |::...|.|..:.|:                .|:.|:|||.....|:.|::||:        |||
 Worm   339 EEVQVENDEVFERSE----------------EEVVTIVRKQLCLALKALLEHGMLSETVVHKRIP 387

  Fly   533 ------AESAASSLMVPFMRCLHPGPPVVPPAVGGDSQFLGLGRAMHAWELVLAYYRLKHGEEYN 591
                  |:|:|                        |.:...|.   |.|:::|.:|.||.|.:..
 Worm   388 GLGCFVAKSSA------------------------DEKSTSLS---HIWDVILYFYNLKTGRDTT 425

  Fly   592 NTPARKLSQSFQLDIVDAQAVTAKQSLLSAVGMILAMHRPYKRSNNAHFKAFVCAGLNSHLLVEW 656
            :.|.|||||||:||.|..:::|:||.||:.:..|::.|...|||.:||:||||.|.||...|..|
 Worm   426 DAPVRKLSQSFKLDHVGGRSITSKQVLLTTIENIISTHARLKRSKDAHWKAFVSAALNEKKLPAW 490

  Fly   657 LNLILSCHELVDTYYSADSYVARTGFRDSLRSIDALSRFDFDLPVDLAIRHFRNI 711
            |.:|....::|:..|::.|||||||..:....::.|.::...||||||:|.|..|
 Worm   491 LRIIFRTRQVVEMCYNSWSYVARTGCEELYTLLEGLHKYSIHLPVDLALRPFEQI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3703	NP_569874.1	RUN	516..703	CDD:280855	66/200 (33%)
rund-1	NP_508136.2	Smc	<45..>256	CDD:224117	89/242 (37%)
		RUN	474..536	CDD:214736	23/61 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163630
Domainoid	1	1.000	157	1.000	Domainoid score	I2539
eggNOG	1	0.900	-	-		E1_KOG3759
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	289	1.000	Inparanoid score	I1700
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45254
OrthoDB	1	1.010	-	-		D255049at33208
OrthoFinder	1	1.000	-	-		FOG0007086
OrthoInspector	1	1.000	-	-		oto19831
orthoMCL	1	0.900	-	-		OOG6_107488
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3919
SonicParanoid	1	1.000	-	-		X5173
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800