DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3704 and Gpn1

DIOPT Version :9

Sequence 1:	NP_569872.1	Gene:	CG3704 / 31043	FlyBaseID:	FBgn0040346	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001121044.1	Gene:	Gpn1 / 688393	RGDID:	1589985	Length:	373	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	183/369 - (49%)
Similarity:	248/369 - (67%)	Gaps:	19/369 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SEGIRESPVCILVLGMAGSGKTTFTQKLIQHAQEK-FNPYVVNLDPACREVPYAAHVDIRDTVNY 79
            :.|..|.|||:|||||||||||||.|:|..|...| ..|||:|||||..|||:.|::||||||.|
  Rat    12 ASGAPELPVCLLVLGMAGSGKTTFVQRLTGHLHNKGCPPYVINLDPAVHEVPFPANIDIRDTVKY 76

  Fly    80 REVMKQYQLGPNGGIVTALNMFTTKMAQFAELVRRAGERGHKWCVIDTPGQIEVFNWSASGSIIT 144
            :||||||.|||||||||:||:|.|:..|..:.:.:| :...::.:||||||||||.|||||:|||
  Rat    77 KEVMKQYGLGPNGGIVTSLNLFATRFDQVMKFIEKA-QNTFRYVLIDTPGQIEVFTWSASGTIIT 140

  Fly   145 EGLATMFPTIVVYVMDVERSACPTTFMSNMLYACSILYKTRLPFLVALNKIDLKDCGFVMDWMTD 209
            |.||:.|||:|:||||..||..|.||||||||||||||||:|||:|.:||.|:.|..|.::||.|
  Rat   141 EALASSFPTVVIYVMDTSRSTNPVTFMSNMLYACSILYKTKLPFIVVMNKTDIIDHSFAVEWMQD 205

  Fly   210 FEAFQEAQEEEHSFVSNLTRTMSLTLDTFYENLRTCGVSAKTGVGFTQLLTKILESVDEYETDYK 274
            |||||:|..:|.::||||||:|||.||.||.:||..||||..|.||.:|..::..:.:|||.:|:
  Rat   206 FEAFQDALNQETTYVSNLTRSMSLVLDEFYSSLRVVGVSAVVGTGFDELCAQVTSAAEEYEREYR 270

  Fly   275 PVYEK-KRQERLAESATGPKPVDHVEEDGHAVPLGLSLQDPPPHTGNSIFLMAPS--LVPESAEI 336
            |.||: |:....|:|....:.::.:.:|..::.|     ||...|..:..::.||  ::......
  Rat   271 PEYERLKKSLASAQSNEQKEQLERLRKDMGSIAL-----DPGASTDGASPVLDPSDLILTRGTLD 330

  Fly   337 EDEEEMEED--------AKGTAEEQNFHSFVQNHLTAQQSKRDK 372
            |::||.:.|        .:.:.||..|.:|:|..: ||..||:|
  Rat   331 EEDEEADSDTDDIDHRVTEESREEPAFQNFMQESI-AQHWKRNK 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3704	NP_569872.1	Gem1	24..199	CDD:224025	114/175 (65%)
CG3704	NP_569872.1	ATP_bind_1	28..268	CDD:281079	146/240 (61%)
Gpn1	NP_001121044.1	GPN1	20..259	CDD:349779	149/239 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354388
Domainoid	1	1.000	299	1.000	Domainoid score	I1396
eggNOG	1	0.900	-	-		E1_KOG1532
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5257
Inparanoid	1	1.050	345	1.000	Inparanoid score	I2251
OMA	1	1.010	-	-		QHG54774
OrthoDB	1	1.010	-	-		D1096688at2759
OrthoFinder	1	1.000	-	-		FOG0005260
OrthoInspector	1	1.000	-	-		oto98785
orthoMCL	1	0.900	-	-		OOG6_101544
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3783
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770