DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3704 and SPBC119.15

DIOPT Version :9

Sequence 1:	NP_569872.1	Gene:	CG3704 / 31043	FlyBaseID:	FBgn0040346	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_595297.1	Gene:	SPBC119.15 / 2540123	PomBaseID:	SPBC119.15	Length:	367	Species:	Schizosaccharomyces pombe

Alignment Length:	354	Identity:	151/354 - (42%)
Similarity:	209/354 - (59%)	Gaps:	45/354 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ESPVCILVLGMAGSGKTTFTQKLIQHAQEKFN-PYVVNLDPACREVPYAAHVDIRDTVNYREVMK 84
            :.|..|:|:||||||||||.|:|..|...|.. ||::|||||.|.:||.|::|||||:||:||||
pombe     6 KKPCAIIVVGMAGSGKTTFMQQLNAHLHSKNKPPYILNLDPAVRNLPYEANIDIRDTINYKEVMK 70

  Fly    85 QYQLGPNGGIVTALNMFTTKMAQFAELV-RRAGERGHKWCVIDTPGQIEVFNWSASGSIITEGLA 148
            ||.|||||||:|:||:|.||..|..::: :||....|  .:||||||||:|.||||||||.:.||
pombe    71 QYNLGPNGGIMTSLNLFVTKFDQVLKILEKRAPTVDH--ILIDTPGQIEIFQWSASGSIICDTLA 133

  Fly   149 TMFPTIVVYVMDVERSACPTTFMSNMLYACSILYKTRLPFLVALNKIDLKDCGFVMDWMTDFEAF 213
            :.:||.:.||:|..|:...:|:||:||||||:|||.:||.::..||.|::|..|...||||||.|
pombe   134 SSWPTCIAYVVDTPRATSTSTWMSSMLYACSMLYKAKLPLIIVYNKCDVQDSEFAKKWMTDFEEF 198

  Fly   214 QEAQEEEH---------SFVSNLTRTMSLTLDTFYENLRTCGVSAKTGVGFTQLLTKILESVDEY 269
            |:|..::.         .::.:|..:|||.|:.||.:|.....|:.||.|....|..:...|.||
pombe   199 QQAVTKDEGMSSEGATSGYMGSLVNSMSLMLEEFYRHLDFVSCSSVTGEGMDDFLEAVKAKVKEY 263

  Fly   270 ETDYKPVYEKKRQ------ERLAESATGPKPVD-HVEEDGHAVPLGLSLQDPPPHTGNSIFLMAP 327
            |.:|.|..|:.::      ||..|:.......| ||.:|...|  ||::.|
pombe   264 EEEYVPEMERMKEIQRQTKERQKEAQLSKLMKDMHVSKDKEDV--GLTVSD-------------- 312

  Fly   328 SLVPESAEIEDEEEM---EEDAKGTAEEQ 353
                  ||.|...|:   :||...|||::
pombe   313 ------AEDEYNGELVDPDEDDGLTAEDR 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3704	NP_569872.1	Gem1	24..199	CDD:224025	99/176 (56%)
CG3704	NP_569872.1	ATP_bind_1	28..268	CDD:281079	123/250 (49%)
SPBC119.15	NP_595297.1	Gem1	6..209	CDD:224025	111/204 (54%)
SPBC119.15	NP_595297.1	ATP_bind_1	13..262	CDD:281079	123/250 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	240	1.000	Domainoid score	I457
eggNOG	1	0.900	-	-		E1_KOG1532
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5257
Inparanoid	1	1.050	261	1.000	Inparanoid score	I745
OMA	1	1.010	-	-		QHG54774
OrthoFinder	1	1.000	-	-		FOG0005260
OrthoInspector	1	1.000	-	-		oto102109
orthoMCL	1	0.900	-	-		OOG6_101544
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R835
SonicParanoid	1	1.000	-	-		X3783
TreeFam	1	0.960	-	-
	14	13.860