DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3704 and gop-2

DIOPT Version :9

Sequence 1:	NP_569872.1	Gene:	CG3704 / 31043	FlyBaseID:	FBgn0040346	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_498118.1	Gene:	gop-2 / 175722	WormBaseID:	WBGene00001661	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	365	Identity:	165/365 - (45%)
Similarity:	223/365 - (61%)	Gaps:	32/365 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAEGVESIKLEALSLSE--------GIRESPVCILVLGMAGSGKTTFTQKL--IQHAQEKFNPYV 55
            |||..|::...:...||        .:.:.| .||||||||||||||.|:|  ..||: |..|||
Worm     1 MAEKAENLPSSSAEASEEPSPQTGPNVNQKP-SILVLGMAGSGKTTFVQRLTAFLHAR-KTPPYV 63

  Fly    56 VNLDPACREVPYAAHVDIRDTVNYREVMKQYQLGPNGGIVTALNMFTTKMAQFAELVRRAGERGH 120
            :|||||..:|||..:|||||||.|:||||::.:||||.|:|.||:..|:..:..||:.:... ..
Worm    64 INLDPAVSKVPYPVNVDIRDTVKYKEVMKEFGMGPNGAIMTCLNLMCTRFDKVIELINKRSS-DF 127

  Fly   121 KWCVIDTPGQIEVFNWSASGSIITEGLATMFPTIVVYVMDVERSACPTTFMSNMLYACSILYKTR 185
            ..|::|||||||.|.|||||||||:.||:..||:|:|::|..|:..||||||||||||||||:|:
Worm   128 SVCLLDTPGQIEAFTWSASGSIITDSLASSHPTVVMYIVDSARATNPTTFMSNMLYACSILYRTK 192

  Fly   186 LPFLVALNKIDLKDCGFVMDWMTDFEAFQEAQEE-EHSFVSNLTRTMSLTLDTFYENLRTCGVSA 249
            |||:|..||.|:....|.:.||.|||.|.||.|: ..|::::|:|::||.||.||..|:|..||:
Worm   193 LPFIVVFNKADIVKPTFALKWMQDFERFDEALEDARSSYMNDLSRSLSLVLDEFYCGLKTVCVSS 257

  Fly   250 KTGVGFTQLLTKILESVDEYETDYKPVYEKKRQERLAESATGPKPVDHVEEDGHAVPLGLSLQDP 314
            .||.||..::|.|.|||:.|:.:|.|:|||...|:........|..|.....|.||
Worm   258 ATGEGFEDVMTAIDESVEAYKKEYVPMYEKVLAEKKLLDEEERKKRDEETLKGKAV--------- 313

  Fly   315 PPHTGNSIFLMAPSLVPE-SAEIED------EEEMEEDAK 347
              |..|.:......|..| :::|:.      :||.||||:
Worm   314 --HDLNKVANPDEFLESELNSKIDRIHLGGVDEENEEDAE 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3704	NP_569872.1	Gem1	24..199	CDD:224025	103/176 (59%)
CG3704	NP_569872.1	ATP_bind_1	28..268	CDD:281079	133/242 (55%)
gop-2	NP_498118.1	Gem1	33..241	CDD:224025	116/209 (56%)
gop-2	NP_498118.1	ATP_bind_1	35..276	CDD:281079	133/242 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167774
Domainoid	1	1.000	260	1.000	Domainoid score	I1067
eggNOG	1	0.900	-	-		E1_KOG1532
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5257
Inparanoid	1	1.050	281	1.000	Inparanoid score	I1755
Isobase	1	0.950	-	0	Normalized mean entropy	S522
OMA	1	1.010	-	-		QHG54774
OrthoDB	1	1.010	-	-		D1096688at2759
OrthoFinder	1	1.000	-	-		FOG0005260
OrthoInspector	1	1.000	-	-		oto17245
orthoMCL	1	0.900	-	-		OOG6_101544
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R835
SonicParanoid	1	1.000	-	-		X3783
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790