DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3704 and gpn1

DIOPT Version :9

Sequence 1:	NP_569872.1	Gene:	CG3704 / 31043	FlyBaseID:	FBgn0040346	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001096245.1	Gene:	gpn1 / 100124802	XenbaseID:	XB-GENE-6454885	Length:	361	Species:	Xenopus tropicalis

Alignment Length:	371	Identity:	180/371 - (48%)
Similarity:	241/371 - (64%)	Gaps:	24/371 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SEGIRESPVCILVLGMAGSGKTTFTQKLIQHAQEKFN-PYVVNLDPACREVPYAAHVDIRDTVNY 79
            :||  ...:|::||||||||||||.|:|..:...|.: |||:|||||..|:|:.|::||||||||
Frog     4 AEG--SGALCLIVLGMAGSGKTTFVQRLAAYLHGKNSPPYVINLDPAVHEIPFPANIDIRDTVNY 66

  Fly    80 REVMKQYQLGPNGGIVTALNMFTTKMAQFAELVRRAGERGHKWCVIDTPGQIEVFNWSASGSIIT 144
            :||||||.|||||||||:||:|.|:..|..:.:.:. ::..::.:||||||||||.|||||:|||
Frog    67 KEVMKQYTLGPNGGIVTSLNLFATRFDQVVKFIEKR-QQNCRYVLIDTPGQIEVFTWSASGAIIT 130

  Fly   145 EGLATMFPTIVVYVMDVERSACPTTFMSNMLYACSILYKTRLPFLVALNKIDLKDCGFVMDWMTD 209
            |.||:.||::||||||..||..|.||||||||||||:|||:|||:|.:||.|:.|..|.::||.|
Frog   131 EALASSFPSVVVYVMDTSRSTNPVTFMSNMLYACSIMYKTKLPFIVVMNKTDIIDHSFAVEWMQD 195

  Fly   210 FEAFQEAQEEEHSFVSNLTRTMSLTLDTFYENLRTCGVSAKTGVGFTQLLTKILESVDEYETDYK 274
            ||.||:|..:|.|:||||||:|||.||.||..||..||||.||.|..:...|:.|:.||||.:|:
Frog   196 FETFQDALNQETSYVSNLTRSMSLVLDEFYSALRVVGVSAVTGAGMEEFFAKVAEAADEYEREYR 260

  Fly   275 PVYEKKRQERLAESATGPK-PVDHVEEDGHAVPL------GLSLQDPPPHTGNSIFLMAPSLVPE 332
            |.|::.|:|...:.....| .::.:..|..:|.|      ||.:..|     :.:.|...:  ||
Frog   261 PEYDRLRKEAEEQQRKQQKEQLERLHRDMGSVALNAGPGAGLEVAGP-----SDLILTRGN--PE 318

  Fly   333 SAEIEDEEEMEED---AKGTAEEQNFHSFVQNHLTAQQSKRDKLQQ 375
            ..|.||.:..:.|   |:...||..|.:|:|.   .|...|.|..|
Frog   319 EEEPEDSDTDDIDHSVAEERLEEPAFQNFLQQ---TQNMYRKKTGQ 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3704	NP_569872.1	Gem1	24..199	CDD:224025	109/175 (62%)
CG3704	NP_569872.1	ATP_bind_1	28..268	CDD:281079	144/240 (60%)
gpn1	NP_001096245.1	ATP_bind_1	14..254	CDD:308588	144/240 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	290	1.000	Domainoid score	I1523
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2475
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005260
OrthoInspector	1	1.000	-	-		oto105480
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3783
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050