Protein Alignment TRAM and LAG1

DIOPT Version :10

• Sequence 1: NP_726710.1
• Gene: TRAM / 31042
• FlyBaseID: FBgn0040340
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_011860.1
• Gene: LAG1 / 856386
• SGDID: S000000995
• Length: 411
• Species: Saccharomyces cerevisiae
• Alignment Length: 307
• Identity: 65/307 - (21%)
• Similarity: 124/307 - (40%)
• Gaps: 70/307 - (22%)

  Fly    31 IISCV-AMVFVVGLMNESTAAFASAFISLHHNVSGEDPSREQPYGKPYTYIAGIKDYCAIFFYTL 94
            |:.|| :..|:.|...||..  ...|:::.:.|.|.|           :|..||||...:|||
Yeast    90 ILVCVYSAYFLSGNRTESNP--LHMFVAISYQVDGTD-----------SYAKGIKDLSFVFFY-- 139

  Fly    95 TCIIMHAIIQEFVLDKISKKLHL-----SKFKLARFNESGQLVAFYLLSFVWGAHVLL-KEGYLG 153
              :|....::||::|.:.:...:     |:.:..|..|....:.:..:|..:|.:::. .:.:|.
Yeast   140 --MIFFTFLREFLMDVVIRPFTVYLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHSDLWLF 202

  Fly   154 QVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYFQKIKTKEEQQPKIVHSISGFTLIVLAY 218
            :...::..:|.....||.|.:::.|.|::......|..|..|.:::.:..:.|.|....||..:|
Yeast   203 KTKPMYRTYPVITNPFLFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHIVTLLLIWSSY 267

  Fly   219 TLSFQRLALVLL--------------TLHYFSELLSHVFQ--LIGVFDREERLAKLRVVNNAVFF 267
            ...|.::.|.:.              ||:|    |:.||.  :.|:|               |||
Yeast   268 VFHFTKMGLAIYITMDVSDFFLSLSKTLNY----LNSVFTPFVFGLF---------------VFF 313

  Fly   268 LIRFATSVIGVLTLYYGIGGVRSLLALGGLIALQGYLVFSFITEQLR 314
            .| :...|:.:..|:..:...|.          :|..|.:|.|:|.:
Yeast   314 WI-YLRHVVNIRILWSVLTEFRH----------EGNYVLNFATQQYK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRAM	NP_726710.1	TRAM1	52..121	CDD:462460	17/73 (23%)
		TLC	124..290	CDD:214789	35/182 (19%)
LAG1	NP_011860.1	LAG1	8..411	CDD:227391	65/307 (21%)