Protein Alignment TRAM and Tram1

DIOPT Version :10

• Sequence 1: NP_726710.1
• Gene: TRAM / 31042
• FlyBaseID: FBgn0040340
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_082449.1
• Gene: Tram1 / 72265
• MGIID: 1919515
• Length: 374
• Species: Mus musculus
• Alignment Length: 388
• Identity: 160/388 - (41%)
• Similarity: 221/388 - (56%)
• Gaps: 36/388 - (9%)

  Fly     1 MAIKPGLGRKTSNKNPPILSHEFVIQNHADIISCVAMVFVVGLMNESTAAFASAFISLHHNVSGE 65
            |||     ||.||||||:|||||::||||||:||:||:|::|||.|.||..|..|::|.:||: .
Mouse     1 MAI-----RKKSNKNPPLLSHEFLLQNHADIVSCLAMLFLLGLMFEVTAKGAIIFVALQYNVT-R 59

  Fly    66 DPSREQPYGKPYTYIAGIKDYCAIFFYTLTCIIMHAIIQEFVLDKISKKLHLSKFKLARFNESGQ 130
            ..:.||.......|..||||...:.||.|..||:||||||:|||||::::|.||.|.::||||||
Mouse    60 PATEEQATESASLYHYGIKDLATVLFYMLVAIIIHAIIQEYVLDKINRRMHFSKTKHSKFNESGQ 124

  Fly   131 LVAFYLLSFVWGAHVLLKEGYLGQVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYFQKIK 195
            |.||||.:.|||..:|:.|.|:.....||..:|.:.|:|..||:::.||||:||..||||||  |
Mouse   125 LSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQTKFFYISQLAYWLHAFPELYFQ--K 187

  Fly   196 TKEEQQPKIVHSISGFTL-IVLAYTLSFQRLALVLLTLHYFSELLSHVFQLIGVFDREERLAKLR 259
            ||:|..|:.:..|..:.. |..||.|:...|.||||.||||.|.|.|:.:|.  :..:|:..|..
Mouse   188 TKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLF--YFSDEKYQKGF 250

  Fly   260 VVNNAVFFLIRFATSVIGVLTLYYGIG-----------GVRSLLA-----LGGLIALQGYLVFSF 308
            .:...:|.|.|..|.::.|||:.:|:.           |..::||     |..:...|.::::.|
Mouse   251 SLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICITQAFMMWKF 315

  Fly   309 ITEQLRAKREAKKEAKREAKLALQTKKPAKTPKDKVKRKKESDLPEADQTS---PSPIKQKLK 368
            |..|||..||.........|     :|||.| |.:..||...:......||   .||..:|.|
Mouse   316 INFQLRRWREHSAFQAPPVK-----RKPAVT-KGRSSRKGTENGVNGTVTSNGADSPRNRKEK 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRAM	NP_726710.1	TRAM1	52..121	CDD:462460	31/68 (46%)
		TLC	124..290	CDD:214789	70/177 (40%)
Tram1	NP_082449.1	TRAM1	47..115	CDD:462460	31/68 (46%)
		TLC	117..326	CDD:214789	80/212 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..374		14/46 (30%)