Protein Alignment TRAM and Tram2

DIOPT Version :9

• Sequence 1: NP_001245456.1
• Gene: TRAM / 31042
• FlyBaseID: FBgn0040340
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_803128.1
• Gene: Tram2 / 170829
• MGIID: 1924817
• Length: 370
• Species: Mus musculus
• Alignment Length: 382
• Identity: 146/382 - (38%)
• Similarity: 214/382 - (56%)
• Gaps: 40/382 - (10%)

  Fly     9 RKTSNKNPPILSHEFVIQNHADIISCVAMVFVVGLMNESTAAFASAFISLHHNVSGEDPSREQPY 73
            |:|  |:.|:.|.||:|.|||||..|:.:..::|||.|.||..|..||...:|:|......|..:
Mouse     5 RRT--KSYPLFSQEFIIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPTADSETVH 67

  Fly    74 GKPYTYIAGIKDYCAIFFYTLTCIIMHAIIQEFVLDKISKKLHLSKFKLARFNESGQLVAFYLLS 138
               |.|  |.||...|.||.:..||.||::||::||||||:|||||.|.::|||||||:.|:|.:
Mouse    68 ---YHY--GPKDLVTILFYVVITIIFHAVVQEYILDKISKRLHLSKVKHSKFNESGQLLVFHLSA 127

  Fly   139 FVWGAHVLLKEGYLGQVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYFQKIKTKEEQQPK 203
            ..|..:|::.||||.....|||.:|...:||..||:::.||||:||.||||||||:  ::|:.|:
Mouse   128 VAWCFYVIVTEGYLTNPRSLWEDYPHVYLSFQVKFFYLGQLAYWLHSLPELYFQKV--RKEEVPR 190

  Fly   204 IVHSISGFTL-IVLAYTLSFQRLALVLLTLHYFSELLSHVFQLIGVFDREERLAKLRVVN--NAV 265
            .:..|..:.| |..||.|:..||.|:||.|.|.:|.|.|:.:|....|....    |:.|  .||
Mouse   191 QLQYICLYLLHITGAYLLNLSRLGLILLLLQYSTEALFHMARLFHFADENNE----RLFNAWAAV 251

  Fly   266 FFLIRFATSVIGVLTLYYGIGGVRSLL-------------ALGGLIAL---QGYLVFSFITEQLR 314
            |.:.|.....:.|||:.:|:..|.:.:             .||.|:.:   |.:|::.||..|||
Mouse   252 FGVTRLFILTLAVLTIGFGLARVENQVFDPEKGNFNTLPCRLGMLLLVCVAQAWLMWRFIHSQLR 316

  Fly   315 AKREAKKEAKREAKLALQTKKPAKTPKDKVKRK---KESDLPEADQTSPSPIKQKLK 368
            ..||..||...:.:::...:.|||.    :||:   .|:.:.:|:..:.|..| |||
Mouse   317 HWREYWKEQSAKRRVSAVPRPPAKL----LKREPGYHENGVVKAENGTSSRTK-KLK 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRAM	NP_001245456.1	TRAM1	52..121	CDD:285576	31/68 (46%)
		TLC	124..290	CDD:214789	68/168 (40%)
Tram2	NP_803128.1	TRAM1	49..110	CDD:285576	30/65 (46%)
		TLC	112..321	CDD:214789	79/214 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	332..370		12/42 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839885
Domainoid	1	1.000	121	1.000	Domainoid score	I5673
eggNOG	1	0.900	-	-		E1_KOG1608
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I3207
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49031
OrthoDB	1	1.010	-	-		D496777at33208
OrthoFinder	1	1.000	-	-		FOG0002124
OrthoInspector	1	1.000	-	-		otm44022
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12371
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1077
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.870