Protein Alignment TRAM and Tram2

DIOPT Version :9

• Sequence 1: NP_001245456.1
• Gene: TRAM / 31042
• FlyBaseID: FBgn0040340
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: XP_002730055.2
• Gene: Tram2 / 100361830
• RGDID: 1589151
• Length: 370
• Species: Rattus norvegicus
• Alignment Length: 382
• Identity: 146/382 - (38%)
• Similarity: 210/382 - (54%)
• Gaps: 40/382 - (10%)

  Fly     9 RKTSNKNPPILSHEFVIQNHADIISCVAMVFVVGLMNESTAAFASAFISLHHNVSGEDPSREQPY 73
            |:|  |:.|:.|.||||.|||||:..:.:..::|||.|.||..|...|...:|||......|
  Rat     5 RRT--KSYPLFSQEFVIHNHADIVFFLVLCVLIGLMFEVTAKIAFLCILPQYNVSVPTADSE--- 64

  Fly    74 GKPYTYIAGIKDYCAIFFYTLTCIIMHAIIQEFVLDKISKKLHLSKFKLARFNESGQLVAFYLLS 138
              ...|..|.||...|.||.|..||:||::||::||||||:|||||.|.::||||||||.|:|.|
  Rat    65 --TVNYHYGPKDLATILFYILITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHLSS 127

  Fly   139 FVWGAHVLLKEGYLGQVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYFQKIKTKEEQQPK 203
            ..|..:|:..||||.....|||.:|...:||..||:::.||||:||.||||||||:  ::|:.|:
  Rat   128 VAWCLYVVATEGYLSNPRSLWEDYPHVYLSFQVKFFYLGQLAYWLHALPELYFQKV--RKEEIPR 190

  Fly   204 IVHSISGFTL-IVLAYTLSFQRLALVLLTLHYFSELLSHVFQLIGVFDREERLAKLRVVN--NAV 265
            .:..|..:.| |..||.|:..||.|:||.|.|.:|.|.|:.:|....|....    |:.|  .||
  Rat   191 QLQYICLYLLHIAGAYLLNLSRLGLILLLLQYSTEALFHMARLFYFADENNE----RLFNAWAAV 251

  Fly   266 FFLIRFATSVIGVLTLYYGIGGVRSLL-------------ALGGLIAL---QGYLVFSFITEQLR 314
            |.:.|.....:.|||:.:|:..|.:.:             .||.|:.:   |.:|::.||..|||
  Rat   252 FGVTRLFIFTLAVLTIGFGLARVENQVFDPEKGNFNTLPCRLGMLLLVCVAQAWLMWRFIHSQLR 316

  Fly   315 AKREAKKEAKREAKLALQTKKPAKTPKDKVKRK---KESDLPEADQTSPSPIKQKLK 368
            ..||..||...:.:::...:.||:.    :||:   .|:.:.:.:..:.|..| |||
  Rat   317 HWREYWKEQSAKRRVSAVPRLPARL----LKREPGFHENGVVKTENGTSSRTK-KLK 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRAM	NP_001245456.1	TRAM1	52..121	CDD:285576	31/68 (46%)
		TLC	124..290	CDD:214789	70/168 (42%)
Tram2	XP_002730055.2	TRAM1	49..110	CDD:285576	30/65 (46%)
		TLC	112..321	CDD:214789	81/214 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343727
Domainoid	1	1.000	120	1.000	Domainoid score	I5614
eggNOG	1	0.900	-	-		E1_KOG1608
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3109
OMA	1	1.010	-	-		QHG49031
OrthoDB	1	1.010	-	-		D496777at33208
OrthoFinder	1	1.000	-	-		FOG0002124
OrthoInspector	1	1.000	-	-		otm46114
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12371
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1077
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870