DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3708 and Nap1l3

DIOPT Version :9

Sequence 1:	NP_569871.2	Gene:	CG3708 / 31039	FlyBaseID:	FBgn0040345	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_620081.1	Gene:	Nap1l3 / 54561	MGIID:	1859565	Length:	544	Species:	Mus musculus

Alignment Length:	486	Identity:	111/486 - (22%)
Similarity:	179/486 - (36%)	Gaps:	158/486 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GMADSAEGVTQEDSHTESRADGISGSLRSLGTYTQESTEPALSPADLPARSRKAFLRH----MIG 63
            |.:.|:...:...|.:.|.:.|.||| .|.|::......       :|..||:|..|.    .:.
Mouse    53 GSSSSSSSSSSSSSSSSSSSSGSSGS-SSNGSHLNRKKR-------VPEPSRRAQRRPSGKLFLD 109

  Fly    64 QLAEPVQNRIRALRHNQLQQVRISEQFFREVYELERRFYGQSCALFDARRDI------------- 115
            :|.:.|:||::|||:.|.:..::...|.|.:::|||::...:..|:|.|..|
Mouse   110 KLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEPTEEECE 174

  Fly   116 -----------------------LEGSVE-----------------------------------P 122
                                   |||..|                                   |
Mouse   175 WNSEEEFSGDEEMQDDTPNEMPPLEGEEEEESCNEKAEVKEEGTHVPEEVPEAKVEEEEAPKETP 239

  Fly   123 PIQTEK-------------------------------------TWPEDPQDALYLDFGNNEELRQ 150
            .::||:                                     ..||:.:|...:...|.|...|
Mouse   240 EVKTEEKDIPKEGAEEKAEEQESSKEIPEVKGEEKADSTDCIDIAPEEKEDVKEVTQANTENKDQ 304

  Fly   151 LRQKLAPVSPT------------------------------TLGVPRFWLTVFQNVPLLSELVQD 185
            ..::..|.:|.                              ..|:|.:||||.:||..|..::|.
Mouse   305 PTEEFTPRAPAREAQKRVPETRPEEGVNIKRARKGKPKKEDPKGIPDYWLTVLKNVDKLGPMIQK 369

  Fly   186 HDEPLLESLMDVRLAYDQD----SYMVIFQFRPNSFLHDSSLLLTKRYFLQHSADPEYPFLFEGP 246
            .|||:|:.|.||.|.:...    .|...|.|.||.:..:.  ||.|.|.::...|...||...|.
Mouse   370 CDEPILKFLSDVSLKFSNPGQPIGYTFEFHFLPNPYFRNE--LLMKTYIIRSKPDHYDPFFAWGW 432

  Fly   247 EIVRCEGCHIHWRDGSNLTLQTVESRR--RNRAHRVTKVMPRESFFRFFAPPQALDLSLADEKTK 309
            ||..|:||.|.||.|.::|:.|..||.  ........:|:|..|||.||:||:...:...:.:..
Mouse   433 EIEECKGCKIDWRRGKDVTVTTTRSRPGITGEIEVQPRVVPNASFFNFFSPPEIPLIGKLEPRED 497

  Fly   310 LILGNDFEVGFLLRTQIVPKAVLFYTGDLVD 340
            .||..|||:|.:|...::.|::.::||::.|
Mouse   498 AILDEDFEIGQILHDNVILKSIYYFTGEIND 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3708	NP_569871.2	NAP	71..336	CDD:279323	91/408 (22%)
Nap1l3	NP_620081.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..109		15/63 (24%)
		NAP	117..>157	CDD:298680	12/39 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	168..345		15/176 (9%)
		NAP	352..524	CDD:279323	59/173 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842129
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1507
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1216172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X426
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.810