DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3708 and Nap1l4

DIOPT Version :9

Sequence 1:	NP_569871.2	Gene:	CG3708 / 31039	FlyBaseID:	FBgn0040345	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001012170.1	Gene:	Nap1l4 / 361684	RGDID:	1305391	Length:	386	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	122/370 - (32%)
Similarity:	201/370 - (54%)	Gaps:	33/370 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GMADSAEGVTQEDSHTESRADGISGSLRSLGTYTQESTEPALSPADLPARSRKAFLRHMIGQLAE 67
            |.|||.| ..:..|:||...|.:..:.:.|....:.....:.:|:.            .|..|.:
  Rat    10 GPADSVE-AAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSS------------YIETLPK 61

  Fly    68 PVQNRIRALRHNQLQQVRISEQFFREVYELERRFYGQSCALFDARRDILEGSVEPPIQTEKTW-- 130
            .|:.||.||:..|::...|..:|:.||::|||::......|||.||:.:.|.|| |...|..|
  Rat    62 AVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVE-PTDAESAWHS 125

  Fly   131 PEDPQDALYLDFGNNEELRQLRQKLAPVSPTTLGVPRFWLTVFQNVPLLSELVQDHDEPLLESLM 195
            ..:..|.|..|..|...:.: ::..|.......|:|.||.|:|:||.:||||||::|||:|:.|.
  Rat   126 ENEEDDKLAGDMKNKVVIAE-KEAAAVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQ 189

  Fly   196 DVRLAYDQD----SYMVIFQFRPNSFLHDSSLLLTKRYFLQHSADPEYPFLFEGPEIVRCEGCHI 256
            |:::.:...    |:::.|.|.||.:.  ::.:|||.|.::...|...||.|||||||.|:||.|
  Rat   190 DIKVKFSDPGQPMSFVLEFHFEPNDYF--TNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTI 252

  Fly   257 HWRDGSNLTLQTVESRRRNR----AHRVTKVMPRESFFRFFAPPQAL-DLSLADEKTKLILGNDF 316
            .|:.|.|:|::|::.:::::    ...:||.:|.||||.||:|.:|. |....||.::..|.:||
  Rat   253 DWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDF 317

  Fly   317 EVGFLLRTQIVPKAVLFYTGDLVDSLSAASPDSRSLSSEAEQEQV 361
            |:|...|.:|||:|||::||:.::     ..|:.....|.|:|::
  Rat   318 EIGHFFRERIVPRAVLYFTGEAIE-----DDDNFEEGEEGEEEEL 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3708	NP_569871.2	NAP	71..336	CDD:279323	102/275 (37%)
Nap1l4	NP_001012170.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28		8/18 (44%)
		NAP	67..337	CDD:366386	101/273 (37%)
		Nuclear localization signal. /evidence=ECO:0000255	265..271		0/5 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	339..386		4/24 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53841
OrthoDB	1	1.010	-	-		D1216172at2759
OrthoFinder	1	1.000	-	-		FOG0000988
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X426
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930