DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3708 and Nap1l2

DIOPT Version :9

Sequence 1:	NP_569871.2	Gene:	CG3708 / 31039	FlyBaseID:	FBgn0040345	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_032697.2	Gene:	Nap1l2 / 17954	MGIID:	106654	Length:	460	Species:	Mus musculus

Alignment Length:	377	Identity:	106/377 - (28%)
Similarity:	172/377 - (45%)	Gaps:	83/377 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GVTQEDSHTESRADGISGSLRSLGTYTQESTEPALSPADLPARSRKAFLRHMIGQLAEPVQNRIR 74
            |.|.|||.:: |..|:.|.|  |.|...||         ||.:                |:.|:.
Mouse    77 GGTDEDSDSD-RPKGLIGYL--LDTDFVES---------LPVK----------------VKCRVL 113

  Fly    75 ALRHNQLQQVRISEQFFREVYELERRFYGQSCALFDARRDILEGSVEPPIQTEKTWPEDPQDAL- 138
            ||:..|.:...:..:|.||.:::||:|......|.:.||.|: .:|..|.:.|..:..|.:|..
Mouse   114 ALKKLQTRAAHLESKFLREFHDIERKFAEMYQPLLEKRRQII-NAVYEPTEEECEYKSDCEDYFE 177

  Fly   139 ------------------------------YLDFGNNEELRQLRQKLAPVSPTTL------GVPR 167
                                          |.|:.:.||..:............:      |:|.
Mouse   178 EEMDEEEETNGNEDGMVHEYVDEDDGYEDCYYDYDDEEEEEEEDDSAGATGGEEVNEEDPKGIPD 242

  Fly   168 FWLTVFQNVPLLSELVQDHDEPLLESLMDVRLAYDQD----SYMVIFQFRPNSFLHDSSLLLTKR 228
            |||||.:||..|:.:::.:|||:|:.|.|:::.....    |:.:.|.|:||.:..:.  ||||.
Mouse   243 FWLTVLKNVEALTPMIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNE--LLTKT 305

  Fly   229 YFLQHSADPEYPFLFEGPEIVRCEGCHIHWRDGSNLTLQTVESRRRNR----AHRVTKVMPRESF 289
            |.|:.......|..:.|..|....||.|.|.:|.|:||:|::.::|:|    ...||:..|::||
Mouse   306 YVLKSKLACYDPHPYRGTAIEYATGCDIDWNEGKNVTLRTIKKKQRHRVWGTVRTVTEDFPKDSF 370

  Fly   290 FRFFAPPQALDLSLADEKTKLILGNDFEVGFLLRTQIVPKAVLFYTGDLVDS 341
            |.||: |..:.|:..||      .:||.:|..|||.|:|::|||::||.::|
Mouse   371 FNFFS-PHGISLNGGDE------NDDFLLGHNLRTYIIPRSVLFFSGDALES 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3708	NP_569871.2	NAP	71..336	CDD:279323	87/309 (28%)
Nap1l2	NP_032697.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..87		5/10 (50%)
		NAP	111..410	CDD:279323	87/308 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..238		2/24 (8%)
		Nuclear localization signal. /evidence=ECO:0000255	346..352		0/5 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842123
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1507
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53841
OrthoDB	1	1.010	-	-		D1216172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X426
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.820