DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MED22 and MED22B

DIOPT Version :9

Sequence 1:	NP_569870.1	Gene:	MED22 / 31038	FlyBaseID:	FBgn0040339	Length:	143	Species:	Drosophila melanogaster
Sequence 2:	NP_001322426.1	Gene:	MED22B / 837310	AraportID:	AT1G07950	Length:	184	Species:	Arabidopsis thaliana

Alignment Length:	129	Identity:	40/129 - (31%)
Similarity:	79/129 - (61%)	Gaps:	9/129 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QSKEALLKSYNARLKDDVRSMLENFEEILKLARRESHSQISKTTQCEQDALEMQVRAANMVRAGE 76
            |.::|||:    |::.|:.|:::||.:|:.:: |.|...:..:    |:...|::||:.||:|.:
plant    57 QKQKALLQ----RVETDITSVVDNFTQIVNVS-RVSDPPVKNS----QETYMMEMRASRMVQAAD 112

  Fly    77 SLMKLVADLKQYLILNDFHSVNEAITNNSQLFRNTQSECDKKLMKLRDEMAMDLYDLEEEYYTS 140
            ||:|||::|||..|.:.|.|:|:.:....:.|.....:.::.|.::.|:.:.:|.:||..||:|
plant   113 SLLKLVSELKQTAIFSGFASLNDHVEQRIEEFDQEAEKTNRLLARIADDASANLKELESHYYSS 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MED22	NP_569870.1	Med22	24..128	CDD:399290	30/103 (29%)
MED22B	NP_001322426.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	56	1.000	Domainoid score	I4045
eggNOG	1	0.900	-	-		E1_KOG3304
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I2454
OMA	1	1.010	-	-		QHG55431
OrthoDB	1	1.010	-	-		D1573728at2759
OrthoFinder	1	1.000	-	-		FOG0004687
OrthoInspector	1	1.000	-	-		mtm1170
orthoMCL	1	0.900	-	-		OOG6_104932
Panther	1	1.100	-	-	LDO	PTHR12434
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840