DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11664 and Mst1

DIOPT Version :9

Sequence 1:	NP_569865.1	Gene:	CG11664 / 31033	FlyBaseID:	FBgn0040341	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_032269.3	Gene:	Mst1 / 15235	MGIID:	96080	Length:	716	Species:	Mus musculus

Alignment Length:	209	Identity:	58/209 - (27%)
Similarity:	83/209 - (39%)	Gaps:	37/209 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 QFLAAGSLFSARYVLTVAHCFKKNTKPEELSVRAGYR-WIAWEFRGKQ--VAGLLRHPKFSPL-- 103
            |....|||...::|||...|.....:|     ..||. |:....:..|  .|.|.|.|....:
Mouse   509 QHFCGGSLVKEQWVLTARQCIWSCHEP-----LTGYEVWLGTINQNPQPGEANLQRVPVAKAVCG 568

  Fly   104 TLRNDIAVLRVKAAISHSHMINYIGLCSRPLTPLNMFAPPQ---ELAGW---------NLMHIAQ 156
            ...:.:.:|:::..:..:|.:..|  |   |.|.....||.   |:|||         .::|:|
Mouse   569 PAGSQLVLLKLERPVILNHHVALI--C---LPPEQYVVPPGTKCEIAGWGESIGTSNNTVLHVA- 627

  Fly   157 PLKSMSVQVEPEKNCRQWFPQISGGVICASA-TMGEGLCYGDSGDPLISGGEVC----GLAIAFR 216
               ||:|....|.|.: :...|....||... .:..|.|.||.|.||......|    ||.|..|
Mouse   628 ---SMNVISNQECNTK-YRGHIQESEICTQGLVVPVGACEGDYGGPLACYTHDCWVLQGLIIPNR 688

  Fly   217 KCGDKRYPALFTDV 230
            .|...|:||:||.|
Mouse   689 VCARPRWPAIFTRV 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11664	NP_569865.1	Tryp_SPc	38..239	CDD:304450	58/209 (28%)
CG11664	NP_569865.1	Tryp_SPc	38..237	CDD:214473	58/209 (28%)
Mst1	NP_032269.3	PAN_1	25..96	CDD:278453
		KR	108..188	CDD:214527
		KR	191..269	CDD:214527
		KR	291..372	CDD:214527
		KR	377..459	CDD:214527
		Tryp_SPc	488..709	CDD:214473	58/209 (28%)
		Tryp_SPc	489..712	CDD:238113	58/209 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833177
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930