DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec22 and SEC22

DIOPT Version :9

Sequence 1:	NP_001259103.1	Gene:	Sec22 / 31030	FlyBaseID:	FBgn0260855	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_172653.1	Gene:	SEC22 / 837737	AraportID:	AT1G11890	Length:	218	Species:	Arabidopsis thaliana

Alignment Length:	216	Identity:	92/216 - (42%)
Similarity:	129/216 - (59%)	Gaps:	7/216 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALLTMIARVIDGLPLVGTMQDDEQVPSGRSILDYQNQAKMLFRKL--GTHSPARCSIETGPYLF 63
            |..:|:||||.|||||...:.|...:|....   |:.|.|.||:.|  |.:..:|.|:|||||:|
plant     1 MVKMTLIARVTDGLPLAEGLDDGRDLPDSDM---YKQQVKALFKNLSRGQNDASRMSVETGPYVF 62

  Fly    64 HYLIENDVCYLVMVDKMYSKRLAFNYLEDLAQEFHANYGRRVNSVTRPYAFIEFDVYIQKAKKQL 128
            ||:||..||||.|.|:.|.|:|||.|||||..||....|..:.:..||||||:||.:|||.||..
plant    63 HYIIEGRVCYLTMCDRSYPKKLAFQYLEDLKNEFERVNGPNIETAARPYAFIKFDTFIQKTKKLY 127

  Fly   129 TDRR--RNISNINTQLQDVQRIMVQNIDDVLQRGTVLAELDTKTQNLSMMSQKYKKDAKLLNRKS 191
            .|.|  |||:.:|.:|.:|.:||.:|:.:||..|..|.::...:..|:..|:.|...||.|||::
plant   128 QDTRTQRNIAKLNDELYEVHQIMTRNVQEVLGVGEKLDQVSEMSSRLTSESRIYADKAKDLNRQA 192

  Fly   192 MYVKAMALGMILLVFIMYFWV 212
            :..|...:.::..|..:.|||
plant   193 LIRKWAPVAIVFGVVFLLFWV 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec22	NP_001259103.1	SNC1	10..192	CDD:227472	82/185 (44%)
		Longin	39..105	CDD:290490	36/67 (54%)
		R-SNARE_SEC22	132..195	CDD:277219	22/64 (34%)
SEC22	NP_172653.1	Longin	3..127	CDD:341428	63/126 (50%)
SEC22	NP_172653.1	R-SNARE_SEC22	133..196	CDD:277219	21/62 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	94	1.000	Domainoid score	I2529
eggNOG	1	0.900	-	-		E1_COG5143
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3597
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1538
OMA	1	1.010	-	-		QHG53513
OrthoDB	1	1.010	-	-		D903466at2759
OrthoFinder	1	1.000	-	-		FOG0004133
OrthoInspector	1	1.000	-	-		oto2900
orthoMCL	1	0.900	-	-		OOG6_101898
Panther	1	1.100	-	-	LDO	PTHR45837
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3400
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840