Protein Alignment Sec22 and VAMP7

DIOPT Version :9

• Sequence 1: NP_001259103.1
• Gene: Sec22 / 31030
• FlyBaseID: FBgn0260855
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001172112.1
• Gene: VAMP7 / 6845
• HGNCID: 11486
• Length: 260
• Species: Homo sapiens
• Alignment Length: 132
• Identity: 33/132 - (25%)
• Similarity: 59/132 - (44%)
• Gaps: 25/132 - (18%)

  Fly    25 QVPSGRSILDYQNQAKMLFRKLGTHSPARCSIETGPYLFHYLIENDVCYLVMVDKMYSKRLAFNY 89
            ::||..:.|.|.:                     |.|||||:.::.:.||.:.|..:.:..|||:
Human    35 KIPSENNKLTYSH---------------------GNYLFHYICQDRIVYLCITDDDFERSRAFNF 78

  Fly    90 LEDLAQEFHANYGRRVNSVTRPYAF-IEFDVYIQKAKKQLTDRR--RNISNINTQLQDVQRIMVQ 151
            |.::.:.|...||.|..:.. |||. .||...:....|..::.:  ..:.....|:.:::.|||:
Human    79 LNEIKKRFQTTYGSRAQTAL-PYAMNSEFSSVLAAQLKHHSENKGLDKVMETQAQVDELKGIMVR 142

  Fly   152 NI 153
            ||
Human   143 NI 144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec22	NP_001259103.1	SNC1	10..192	CDD:227472	33/132 (25%)
		Longin	39..105	CDD:290490	16/65 (25%)
		R-SNARE_SEC22	132..195	CDD:277219	6/24 (25%)
VAMP7	NP_001172112.1	Longin	29..104	CDD:316307	24/90 (27%)
		SNARE	124..>144	CDD:328933	4/19 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53513
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820