DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec22 and Vamp4

DIOPT Version :9

Sequence 1:	NP_001259103.1	Gene:	Sec22 / 31030	FlyBaseID:	FBgn0260855	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_001102326.1	Gene:	Vamp4 / 364033	RGDID:	1309753	Length:	141	Species:	Rattus norvegicus

Alignment Length:	156	Identity:	36/156 - (23%)
Similarity:	68/156 - (43%)	Gaps:	34/156 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 PYLFHYLIENDVCYLVMVDKMYSKRLAFNYLEDLAQEFHANYGRRVNSVTRPYAFIEFDVYIQ-K 123
            |....:|.::||...|..::.       |.|||.:.|                   |.|.::: .
  Rat     3 PKFKRHLNDDDVTGSVKSERR-------NLLEDDSDE-------------------EEDFFLRGP 41

  Fly   124 AKKQLTDRRRNISNINTQLQDVQRIMVQNIDDVLQRGTVLAELDTKTQNLSMMSQKYKKDAKLLN 188
            :..:...|...|.::..|:.:|..:|.:||..|::||..|.||..|:::||..:..:...:|.|.
  Rat    42 SGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLR 106

  Fly   189 RKSMY-------VKAMALGMILLVFI 207
            |:..:       :.|:|..::||:.|
  Rat   107 RQMWWRGCKIKAIMALAAAILLLMII 132

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec22	NP_001259103.1	SNC1	10..192	CDD:227472	31/132 (23%)
		Longin	39..105	CDD:290490	10/44 (23%)
		R-SNARE_SEC22	132..195	CDD:277219	18/69 (26%)
Vamp4	NP_001102326.1	R-SNARE_VAMP4	50..116	CDD:277222	18/65 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810