DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sec22 and sec22bb

DIOPT Version :9

Sequence 1:	NP_001259103.1	Gene:	Sec22 / 31030	FlyBaseID:	FBgn0260855	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_001315455.1	Gene:	sec22bb / 327277	ZFINID:	ZDB-GENE-030131-5488	Length:	219	Species:	Danio rerio

Alignment Length:	219	Identity:	125/219 - (57%)
Similarity:	157/219 - (71%)	Gaps:	6/219 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALLTMIARVIDGLPLVGTMQDDEQ--VPSGRSILDYQNQAKMLFRKLGTHSPARCSIETGPYLF 63
            |.|||||||:.|||||..:||:|||  ...||.:..||:|||.|||||...||.||::|.|...|
Zfish     1 MVLLTMIARLADGLPLAASMQEDEQGSEKMGRDLQQYQSQAKQLFRKLNEQSPNRCTLEAGSMSF 65

  Fly    64 HYLIENDVCYLVMVDKMYSKRLAFNYLEDLAQEFHANYGRRVNSVTRPYAFIEFDVYIQKAKKQL 128
            ||:||..|||||:.:..:.|:|||.|||||..|||..:|::|.:|:|||:|||||.||||.||..
Zfish    66 HYVIEKGVCYLVLCEAGFPKKLAFAYLEDLQAEFHEQHGKKVPTVSRPYSFIEFDTYIQKTKKSY 130

  Fly   129 TD--RRRNISNINTQLQDVQRIMVQNIDDVLQRGTVLAELDTKTQNLSMMSQKYKKDAKLLNRKS 191
            .|  .|||:|||||:|||||||||.||::|||||..|:.||:|..|||.:|:||:.|||.||.:|
Zfish   131 IDSRARRNLSNINTELQDVQRIMVANIEEVLQRGEALSALDSKASNLSSLSKKYRSDAKYLNTRS 195

  Fly   192 MYVKAMALGMILLVFIMY--FWVL 213
            .|.|..|.|:..::.|:|  ||.|
Zfish   196 TYAKLAAGGVFFIMLIVYIRFWWL 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec22	NP_001259103.1	SNC1	10..192	CDD:227472	107/185 (58%)
		Longin	39..105	CDD:290490	36/65 (55%)
		R-SNARE_SEC22	132..195	CDD:277219	41/62 (66%)
sec22bb	NP_001315455.1	SNC1	12..192	CDD:227472	105/179 (59%)
		Longin	41..107	CDD:290490	36/65 (55%)
		R-SNARE_SEC22	136..199	CDD:277219	41/62 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595885
Domainoid	1	1.000	102	1.000	Domainoid score	I6800
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3597
Inparanoid	1	1.050	245	1.000	Inparanoid score	I3263
OMA	1	1.010	-	-		QHG53513
OrthoDB	1	1.010	-	-		D569556at33208
OrthoFinder	1	1.000	-	-		FOG0004133
OrthoInspector	1	1.000	-	-		otm25842
orthoMCL	1	0.900	-	-		OOG6_101898
Panther	1	1.100	-	-	LDO	PTHR45837
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6269
SonicParanoid	1	1.000	-	-		X3400
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940