Protein Alignment Sec22 and Sec22c

DIOPT Version :10

• Sequence 1: NP_001259103.1
• Gene: Sec22 / 31030
• FlyBaseID: FBgn0260855
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_848792.2
• Gene: Sec22c / 215474
• MGIID: 2447871
• Length: 303
• Species: Mus musculus
• Alignment Length: 208
• Identity: 61/208 - (29%)
• Similarity: 94/208 - (45%)
• Gaps: 20/208 - (9%)

  Fly     1 MALLTMIARVIDGLPLVGTMQDDEQVPSGRSILDYQNQAKMLFRKLGTHSPARCSIETGPYLFHY 65
            |.|...|.||.|||||..:    ......:..|:.:.|.|.|.::|..| |.|...|:..:|.::
Mouse     3 MILFASIVRVRDGLPLSAS----TDFYYAQEFLECRRQLKTLAQRLARH-PGRGCAESCDFLIYF 62

  Fly    66 LIENDVCYLVMVDKMYSKRLAFNYLEDLAQEFHANYGRR-VNSVTRPYAFIEFDVYIQKAKKQLT 129
            ....||..:.:..:.....:||.:||.|..:|.|:|... |...:|||||:|||..|||.|...
Mouse    63 SSSGDVACMAICSRQCPAAMAFCFLEALWWDFIASYDTTCVGLASRPYAFLEFDSVIQKTKWHF- 126

  Fly   130 DRRRNISNINTQLQDVQRIMVQNIDDVLQRGTVLAELDTKTQN--LSMMSQKYKKDAKLLNRKSM 192
             ...:.|.:.:.|:.:|..:      ..|...||:..||...|  |:..:..:.:.|..|..|.:
Mouse   127 -NHMSSSQMKSGLEKIQEEL------EFQPPAVLSLEDTDVANGMLNGHTPVHSEPAPNLRMKPV 184

  Fly   193 YVKAMALGMILLV 205
                .|||::.||
Mouse   185 ----TALGVLSLV 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec22	NP_001259103.1	Longin	3..127	CDD:341428	42/124 (34%)
		R-SNARE_SEC22	132..195	CDD:277219	13/64 (20%)
Sec22c	NP_848792.2	Longin	5..123	CDD:341428	41/122 (34%)