DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec22 and vamp7

DIOPT Version :9

Sequence 1:	NP_001259103.1	Gene:	Sec22 / 31030	FlyBaseID:	FBgn0260855	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	XP_031746113.1	Gene:	vamp7 / 100216181	XenbaseID:	XB-GENE-963013	Length:	224	Species:	Xenopus tropicalis

Alignment Length:	193	Identity:	54/193 - (27%)
Similarity:	95/193 - (49%)	Gaps:	27/193 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 QVPSGRSILDYQNQAKMLFRKLGTHSPARCSIETGPYLFHYLIENDVCYLVMVDKMYSKRLAFNY 89
            ::||..:.|.|.:                     |.|||||:.::.:.||.:.|..:.:..|||:
Frog    39 KIPSENNKLTYSH---------------------GSYLFHYICQDRIIYLCITDDDFERSRAFNF 82

  Fly    90 LEDLAQEFHANYGRRVNSVTRPYAF-IEFDVYIQKAKKQLTDRRR--NISNINTQLQDVQRIMVQ 151
            |.::.:.|...||.|..:.. |||. .||...|....|..::.:.  .::....|:.:::.|||:
Frog    83 LNEIKKRFQTTYGSRAQTAL-PYAMNSEFSSVIAAQLKYHSENKSIDRVAETQAQVDELKGIMVR 146

  Fly   152 NIDDVLQRGTVLAELDTKTQNLSMMSQKYKKDAKLLNRKSMYVKAMALGMIL-LVFIMYFWVL 213
            |||.|.|||..|..|..||::|...|..:|..::.|.| :|.:|.:.|.:|: :|.|:..:::
Frog   147 NIDLVAQRGERLELLIDKTESLVDSSVTFKTTSRNLAR-AMCMKNLKLTIIIAIVTIVIIYII 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec22	NP_001259103.1	SNC1	10..192	CDD:227472	48/169 (28%)
		Longin	39..105	CDD:290490	16/65 (25%)
		R-SNARE_SEC22	132..195	CDD:277219	21/64 (33%)
vamp7	XP_031746113.1	Longin	8..120	CDD:341428	27/102 (26%)
vamp7	XP_031746113.1	R-SNARE_VAMP7	128..192	CDD:277224	22/64 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000