Protein Alignment Rbf and Rbl2

DIOPT Version :9

• Sequence 1: NP_525036.2
• Gene: Rbf / 31027
• FlyBaseID: FBgn0015799
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: XP_006255261.1
• Gene: Rbl2 / 81758
• RGDID: 3541
• Length: 1136
• Species: Rattus norvegicus
• Alignment Length: 1154
• Identity: 286/1154 - (24%)
• Similarity: 453/1154 - (39%)
• Gaps: 366/1154 - (31%)

  Fly     2 SEPDPQELGA----EVVSGLVATSDDRLE-------MINAEYTNLCRDLNMDRQTELQGYETYLE 55
            |.|.|....|    |...|..|   ||.:       .|...:..||..||||.....:.:.:|..
  Rat     8 SSPPPPAAAASSEEEEEDGDTA---DRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRS 69

  Fly    56 VSQRCSMEGTASHWMCCAIYTACRRTSTPTVTGQNAVVKGNCVSLNNLLRCCKMSIYEFKTKIKQ 120
            :|:..::||...||:.||:|.|||: |.|||:  ....:||.|||..:|||.:.|:.||..|:|:
  Rat    70 MSESYTLEGNDLHWLACALYVACRK-SVPTVS--KGTAEGNYVSLTRILRCSEQSLIEFFNKMKK 131

  Fly   121 WCDMANLPQEFVNEIEDLDRKFSITFMLHKRFRIIMDMIFSCPPNEKKHSKYISLHGNHAHGK-C 184
            |.||||||..|....|.|:|.|:::.::.|::..|...||..|..|:...:    .|.....: |
  Rat   132 WEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQ----RGRKQRRQPC 192

  Fly   185 SYIKLDDICWRLFLCAKNQKPSNTVDLVTSYNLMICCIDLIYNNVL-AEKRTDLINPKFEGLPSN 248
            :..::...||.||:.||...|..:.|||.||:|::|.:||:|.|.| ...|.:|:||.|:|:..:
  Rat   193 TTSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGVSED 257

  Fly   249 WTELDFR--HNPHCILSNFCDMTE----EAKAMKATTFRQIMSSFFQASTIYGNKDTMLGLLANE 307
            ....|..  .:|.|::...|.:.:    |||.:|...::..:...|:...:.|.::.:.|.|...
  Rat   258 GHPRDSHPSSDPPCVIEKLCSLHDGLVLEAKGIKQHFWKPYIRKLFEKKLLRGKEENLTGFLEPG 322

  Fly   308 NFERNLKSLNISYEQYVLSVGEFDERILSAYDA-------------------GEHTALND----- 348
            ||..:.|::|.:||:|||:.|..||||....||                   .|.|.:.|
  Rat   323 NFAESFKAVNKAYEEYVLATGSLDERIFLGEDAEEEVGTLSRCVSAASGTESAERTQMRDILQQH 387

  Fly   349 ----QSLR--PPVTPLTRKQDLPAQPAMAGDKFEPVRNATNNVKQLSAF--GRITEPTDFVKQ-- 403
                ::||  .|:|.:...|:  ..|.:.     ||..||:::.:|...  |....|::.::|
  Rat   388 LDKSKTLRVCNPLTGVRYVQE--NSPCVT-----PVSTATHSLNRLHTMLAGLRNAPSEKLEQIL 445

  Fly   404 ------AGEEVIAKLLSIIEEIEQKF-----LAKYPSTEAKSRFQLAKSFFFYLLDQILQAEIRN 457
                  ....:..:|..:.|...|.|     ::......|...|:.|:..::.:|:.:::.|.:.
  Rat   446 RSCSRDPTRAIADRLREMYEIYSQHFQPDENVSNCAKEMANKHFRFAEMLYYKVLESVIEQEQKR 510

  Fly   458 KPDIDLKRLLVQKVSLVIFNITLMACCVELVLEAYKTELKFPWVLDCFSISAFEFQKIIEIVVRH 522
            ..|:||..:|.|..    |:.:|:|||:|:|..:||....||::.:.|.:..:.|.|:||:.:|
  Rat   511 LGDMDLSGVLEQDA----FHKSLLACCLEVVAFSYKPPGNFPFIAEIFDVPHYHFYKVIEVFIR- 570

  Fly   523 GSHEGCLNRSLIKHLNSIEETCLERLAWARNSTVWEMIASAQLPLPTWLMV----NLDR------ 577
             :.:| |.|.::||||.|||..|:.|||...|.:|:.|...:..:||...|    ||:|
  Rat   571 -AEDG-LCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVTPPHNLERTDEIYI 633

  Fly   578 ----------------------------------------------------------------- 577
                                                                             
  Rat   634 AGSPLTPRRVGEVRTDAGGLGRSVTSPTTLYDRYSSPTVSTTRRRLFESDSPSEGSTAGRIPPQP 698

  Fly   578 ----------------------------------------------------------------- 577
                                                                             
  Rat   699 LVNAVPVQNVSGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVG 763

  Fly   578 ---------------------------------AAGP---------------------------- 581
                                             ..||
  Rat   764 GQAQAVTGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNQGQPLTSSSIRPRK 828

  Fly   582 ---LQIFLRKVYLLGWLRIQKLCSELSLCEKTPESIWHIFEHSITHETELMKDRHLDQNIMCAIY 643
               |.:|.||||.|..:|::.||::|.:.::..:.||..||.||....|||.||||||.:|||||
  Rat   829 TSSLSLFFRKVYYLAGVRLRDLCTKLDISDELRKKIWTCFEFSIVQCPELMMDRHLDQLLMCAIY 893

  Fly   644 IYIRVKRMEDPKFSDIMRAYRNQPQAVNSVYREVFI--------------------DIN-----E 683
            :..:|.: ||..|.:|||.||.||||.:.|||.|.|                    ::|     .
  Rat   894 VMAKVTK-EDKSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSCENRSHQNSPTELNTDRASR 957

  Fly   684 DGEPKVK---------------------------------DIIHFYNHTYVPLMRQFVIDYLNVT 715
            |..|.::                                 |:|.|||:.|...::.|.:.|....
  Rat   958 DSSPVMRSNSTLPVPQPSSAPPTPTRLTGANSDIEEEERGDLIQFYNNIYRKQIQTFAMKYSQAN 1022

  Fly   716 PDVSGRASDLQLSPHPKERAAQPKKV--TQSHSLFVSQMSKNEIQQSPNQMV-YSFCRSPAKDLQ 777
               |.:.....|||:|..|...|::|  :|||.:::|. .|||...||.:.: |.|..||:|.|:
  Rat  1023 ---SQQMDTPPLSPYPFVRTGSPRRVQLSQSHPIYISP-HKNEAMLSPREKIFYYFSNSPSKRLR 1083

  Fly   778 AMNEKVRGG-----KR--MLSFGDE-PGLGTMAETKRSKISQVKAVMDD 818
            .:|..:|.|     ||  :|..|.| |......|...:.:.:::.|.:|
  Rat  1084 EINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVAND 1132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbf	NP_525036.2	DUF3452	90..225	CDD:288762	48/135 (36%)
		RB_A	376..560	CDD:280101	55/198 (28%)
		RB_B	582..704	CDD:280100	58/179 (32%)
Rbl2	XP_006255261.1	DUF3452	101..233	CDD:288762	48/135 (36%)
		Effector_1	<323..>433	CDD:282387	30/116 (26%)
		RB_A	414..606	CDD:280101	55/203 (27%)
		RB_B	831..1011	CDD:280100	58/180 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341022
Domainoid	1	1.000	112	1.000	Domainoid score	I6050
eggNOG	1	0.900	-	-		E1_KOG1010
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4098
Inparanoid	1	1.050	437	1.000	Inparanoid score	I1633
OMA	1	1.010	-	-		QHG46367
OrthoDB	1	1.010	-	-		D113612at2759
OrthoFinder	1	1.000	-	-		FOG0002362
OrthoInspector	1	1.000	-	-		otm44553
orthoMCL	1	0.900	-	-		OOG6_103769
Panther	1	1.100	-	-	LDO	PTHR13742
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2053
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770