| Sequence 1: | NP_525036.2 | Gene: | Rbf / 31027 | FlyBaseID: | FBgn0015799 | Length: | 845 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001310537.1 | Gene: | RBL2 / 5934 | HGNCID: | 9894 | Length: | 1139 | Species: | Homo sapiens |
| Alignment Length: | 1162 | Identity: | 291/1162 - (25%) |
|---|---|---|---|
| Similarity: | 459/1162 - (39%) | Gaps: | 379/1162 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 SEPDPQELGAEVVSGLVATSDDRLE-----------MINAEYTNLCRDLNMDRQTELQGYETYLE 55
Fly 56 VSQRCSMEGTASHWMCCAIYTACRRTSTPTVTGQNAVVKGNCVSLNNLLRCCKMSIYEFKTKIKQ 120
Fly 121 WCDMANLPQEFVNEIEDLDRKFSITFMLHKRFRIIMDMIFSCPPNEKKHSKYISLHGNHAHGK-C 184
Fly 185 SYIKLDDICWRLFLCAKNQKPSNTVDLVTSYNLMICCIDLIYNNVL-AEKRTDLINPKFEGLPSN 248
Fly 249 WTELDFR--HNPHCILSNFCDMTE----EAKAMKATTFRQIMSSFFQASTIYGNKDTMLGLLANE 307
Fly 308 NFERNLKSLNISYEQYVLSVGEFDERILSAYDAGEH-----TALN-------------------- 347
Fly 348 ---DQSLRPPVTPLTR----KQDLPAQPAMAGDKFEPVRNATNNVKQLSAF--GRITEPTDFVKQ 403
Fly 404 --------AGEEVIAKLLSIIEEIEQKFLAKYPSTE--------AKSRFQLAKSFFFYLLDQILQ 452
Fly 453 AEIRNKPDIDLKRLLVQKVSLVIFNITLMACCVELVLEAYKTELKFPWVLDCFSISAFEFQKIIE 517
Fly 518 IVVRHGSHEGCLNRSLIKHLNSIEETCLERLAWARNSTVWEMIASAQLPLPTWLMV----NLDRA 578
Fly 579 -----AG---------------------------------------------------------- 580
Fly 581 ----------------------------------------------------------------P 581
Fly 582 LQI-------------------------------------------------------------- 584
Fly 585 ------------FLRKVYLLGWLRIQKLCSELSLCEKTPESIWHIFEHSITHETELMKDRHLDQN 637
Fly 638 IMCAIYIYIRVKRMEDPKFSDIMRAYRNQPQAVNSVYREVFI----------------------D 680
Fly 681 INE-----DGEPKVK---------------------------------DIIHFYNHTYVPLMRQF 707
Fly 708 VIDYLNVTPDVSGRASDLQLSPHPKERAAQPKKV--TQSHSLFVSQMSKNEIQQSPNQMV-YSFC 769
Fly 770 RSPAKDLQAMNEKVRGG-----KR--MLSFGDE-PGLGTMAETKRSKISQVKAVMDD 818 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Rbf | NP_525036.2 | DUF3452 | 90..225 | CDD:288762 | 48/135 (36%) |
| RB_A | 376..560 | CDD:280101 | 57/201 (28%) | ||
| RB_B | 582..704 | CDD:280100 | 58/255 (23%) | ||
| RBL2 | NP_001310537.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..45 | 7/36 (19%) | |
| DUF3452 | 104..236 | CDD:288762 | 48/135 (36%) | ||
| Pocket, binds E1A | 417..1024 | 127/617 (21%) | |||
| Domain A | 417..616 | 58/208 (28%) | |||
| RB_A | 417..609 | CDD:280101 | 57/201 (28%) | ||
| Spacer | 617..827 | 11/209 (5%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 654..678 | 0/23 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 810..832 | 0/21 (0%) | |||
| Domain B | 828..1024 | 58/196 (30%) | |||
| RB_B | 835..1017 | CDD:280100 | 57/182 (31%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 933..999 | 3/65 (5%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165147370 | |
| Domainoid | 1 | 1.000 | 111 | 1.000 | Domainoid score | I6234 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1010 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H4098 | |
| Inparanoid | 1 | 1.050 | 449 | 1.000 | Inparanoid score | I1622 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG46367 | |
| OrthoDB | 1 | 1.010 | - | - | D113612at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002362 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40415 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103769 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR13742 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3203 |
| SonicParanoid | 1 | 1.000 | - | - | X2053 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.800 | |||||