DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16989 and AT4G38120

DIOPT Version :9

Sequence 1:	NP_001284761.2	Gene:	CG16989 / 31026	FlyBaseID:	FBgn0025621	Length:	1045	Species:	Drosophila melanogaster
Sequence 2:	NP_001328438.1	Gene:	AT4G38120 / 829968	AraportID:	AT4G38120	Length:	1168	Species:	Arabidopsis thaliana

Alignment Length:	1198	Identity:	246/1198 - (20%)
Similarity:	414/1198 - (34%)	Gaps:	343/1198 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLEAESRTDQEEADRDS--HLQLVREVDHNVGVPVGVAAYRLQQLIAGVRARGHHDLLRL----W 65
            |:.|.|.....|...|.  .|.||.:.|....:||   :....|||..|.||   .|.:|    |
plant    47 LISAVSHLPLHELTSDCLFLLDLVSKADGPDWIPV---SRHTCQLIHDVCAR---LLFQLNSSSW 105

  Fly    66 QLWLNELILAKKIILVRSHLLIEELLAG--TELKPSVETVNLMLTVLKSTPKE-NLAGFWPRLSA 127
            .|.|:......:.:| |..:......|.  :.::|.::....:..:....|:. :|..|..|:..
plant   106 PLLLHSFASVLEFLL-RQPMPSSPYSAAYFSRIEPVIQCFETLRRLAPMHPENIHLVKFLVRVVP 169

  Fly   128 LTHAKDMDVALLLLQCQDRVL----AELEESP------EVAEHNQGLVNSLINMHFEGRWLVAKE 182
            |.|             ||.||    :..:.||      ::.:.|:...:..:.....||.....|
plant   170 LLH-------------QDLVLSYGFSNQDPSPTLLVEKKLPQQNRLWDSMALAFDMFGRAFSLSE 221

  Fly   183 QL-PLLLAQ-SLQLIQKLVTRQPDYAAQR-------------------VPELMGLVQC------- 219
            .| |..::| :|::::|::    |..|.:                   |.|::..::|
plant   222 SLFPTDVSQCTLEVLRKVM----DVLASKGQLVEDRFMWSFYSCLLGCVHEVLTNIKCPVSDHVL 282

  Fly   220 --------YLQYGAEGETHLKPRKLPPAQQSAAYGQEKEEEDQLLAQMSRPCGRKNKVRKMRSLA 276
                    :..:|..|.        |....|.....:|....:|...:|               .
plant   283 SFIASLRMFFCFGLTGP--------PQLSVSDVVHNDKHLNVKLSPLIS---------------G 324

  Fly   277 KQRNQAVNEHHEPNPRERLVLMGNQDYG-----CLTGDSGENG-LPSDSDQQQTENK---HHRHQ 332
            ..:|.....:..|:.|:|..|...|...     ....|||.:. :.||||...::..   .:..|
plant   325 VSKNAKNTPYRPPHLRKRDDLNTRQPVSSSWRRLSAHDSGSSDVISSDSDFSDSDGSVPDSYFAQ 389

  Fly   333 EAKVRISALHLLSTLTNQLPRRSFYGYWHVLFPDGDA------GGTPHLLLLGLKDTNFRCRALA 391
            .:||||:|:..:..|. |...:||...|..|||..|.      ..|  |:...|.|.:.:.|..:
plant   390 SSKVRIAAIVCIQDLC-QADSKSFTTQWVTLFPTSDVLKPRKFEAT--LMTCLLFDPHLKVRIAS 451

  Fly   392 LQVGAQLLYGSKAFLSQACSLGPS----NFTPFAVSLASSVLTAYRILIAILEREYTPPVLTQCL 452
            ....|.::.|..:...|......|    :|.|.:.||...::..:..::.::..:....:|.|..
plant   452 ASALATMMDGPSSIFLQVAEYKESTKYGSFMPLSNSLGLILMQLHTGILHLIHSDNHGRLLIQLF 516

  Fly   453 KCLAVLVQATPFHQLEMGFVYEFVGHVKKLIKSSDPPVAVSALLVMEMLVGTSKLTPEIASSIGL 517
            |.|.:|:.:||:.::                                    ..:|.|::..|:
plant   517 KILLLLISSTPYSRM------------------------------------PGELLPKVIMSL-- 543

  Fly   518 APSQRNLQMEHASTAETYQELCDSDAEMELEEG--------DEQQQPSQNNVVNPVHTVSPTIPR 574
                      ||...|.:....|....:....|        ...|....|.:::...........
plant   544 ----------HARINEGFPFKNDKTGLLVAAIGCLSAAFSTFPPQMKVHNMLLDETSAGFNGCEW 598

  Fly   575 NSWLLRQVLRCLEGMRIPSAVRLECFQVLQAMA-THIGLLRGHQVRLSRVI-----SAGLTDPAT 633
            ||.:|..:.|..|.....|.. :|..|||:|:| .:..|:..:..|:|.::     ||.:.|..|
plant   599 NSGVLSTLFRFAEQFSDASTC-IEALQVLRAVALNYPTLVPAYWERVSILVYKLLQSAVVEDSPT 662

  Fly   634 DVKLYAARCLDSVGY-----------------------------QLGRLLPEPAERELQMSFWLT 669
            ..|   :...:||||                             |..||:..|...:...|..::
plant   663 TWK---SSVRESVGYNGDKVLTAAIKVLDGCLRAISGFKGTEDLQYDRLMDTPFTSDCIRSIRIS 724

  Fly   670 LLPA-----TYEAYDSAGFSLKCALCD------------ALSNMGAISFERLPDGQRTALLAFLS 717
            ..|:     |.|....||       ||            .|.:..|:        .|:..:...:
plant   725 SAPSYGFDNTQEPIFQAG-------CDQWSEAIRKHIVLVLHHGSAV--------VRSTTVTCFA 774

  Fly   718 GCASDD---------------------HEET-LVRVAALRAMAVYVLHPSLRTDLGFVEN---AA 757
            |..|..                     |::| .||.||.||:.|....|.........|.   |.
plant   775 GITSSIFSAFNKQEKDFITSSIITAALHDKTPSVRSAACRAIGVISCFPETSLSAEIYEKFILAV 839

  Fly   758 ELTLRILGDSQLLARIKAAWALGNISDALVAGIPNQT---ERISAELLERLIQAATKSCADNDKV 819
            |...|   ||....||.|:|||.|:.|||...:.:::   .:.::::::.||:.|.:...|.|||
plant   840 EANTR---DSLTSVRITASWALANLCDALRYRVDDRSFEGLKTTSQVVDALIECALRLTEDGDKV 901

  Fly   820 RANAVRALGNLLQILQV------------------QPLGNGELMQVA---------MSKLLDCVT 857
            ::|||||||::.:.:::                  |...|...:..|         :...|.|||
plant   902 KSNAVRALGSISKYVKLRCMTSIKSVDQDVLPFPHQQSSNSHHLSCAVDTRWLERTVQAFLSCVT 966

  Fly   858 LPGNAKVKWNACYVIGNLVKHRAFFANNRL-------AGILFPTLCQLVVQHANFKVRTNAAGVL 915
             .||.||:||.|:.:.||      |:|..:       |..:|..|..|:...:|||:|..||..|
plant   967 -TGNVKVQWNVCHALSNL------FSNETVKLQDMDWAPSVFSILLLLLRDASNFKIRIQAASAL 1024

  Fly   916 LQVKQREDFSAHFPLLWRSLLDALVRSNVLESFE--------EYNHRDALQQQLCLAIAHLLLLA 972
            ........:...||.:.:.:      .:.|:|..        .:.::.:|:.||...:.|||.|.
plant  1025 AVPATPLAYGRSFPDVVKGV------EHTLQSLHSDRETTPANFKYKRSLENQLTSTMLHLLSLV 1083

  Fly   973 RSSDLPMMRESL--EEDRLEEVQATWRR 998
            .|.....:.|.|  :...|||    |.|
plant  1084 SSCHFEALSEFLIRKASFLEE----WLR 1107

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16989	NP_001284761.2	DUF4042	335..511	CDD:404188	36/185 (19%)
		HEAT repeat	712..745	CDD:293787	11/54 (20%)
		SRP1	721..>830	CDD:227396	41/136 (30%)
		HEAT repeat	755..785	CDD:293787	12/32 (38%)
		HEAT repeat	800..829	CDD:293787	13/28 (46%)
		HEAT repeat	845..875	CDD:293787	12/38 (32%)
		HEAT repeat	889..917	CDD:293787	10/27 (37%)
		HEAT repeat	928..950	CDD:293787	4/29 (14%)
AT4G38120	NP_001328438.1	DUF4042	392..577	CDD:372531	42/235 (18%)
		HEAT repeat	787..824	CDD:293787	9/36 (25%)
		HEAT repeat	834..864	CDD:293787	12/32 (38%)
		HEAT repeat	886..911	CDD:293787	13/24 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D106835at2759
OrthoFinder	1	1.000	-	-		FOG0007369
OrthoInspector	1	1.000	-	-		oto3263
orthoMCL	1	0.900	-	-		OOG6_104402
Panther	1	1.100	-	-	LDO	PTHR13366
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5488
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.010