Protein Alignment CG16989 and LOC1269718

DIOPT Version :10

• Sequence 1: NP_569860.3
• Gene: CG16989 / 31026
• FlyBaseID: FBgn0025621
• Length: 1045
• Species: Drosophila melanogaster
• Sequence 2: XP_308367.5
• Gene: LOC1269718 / 1269718
• VectorBaseID: AGAMI1_014473
• Length: 1139
• Species: Anopheles gambiae
• Alignment Length: 1030
• Identity: 337/1030 - (32%)
• Similarity: 503/1030 - (48%)
• Gaps: 162/1030 - (15%)

  Fly    70 NELILAKKIILVRSHLLIEELLAGTELKPSVETV-NLMLTVLKSTPKENLAGFWPRLSALTHAKD 133
            :||.|| .::.:.|.|:..|||....|:|.:..| |.:|.::          |..|..:.|....
Mosquito   172 SELYLA-ALLCLESILICSELLGAEVLEPYLPVVGNAVLDLI----------FKARTESFTELAY 225

  Fly   134 MDVALLLLQCQDRVLAELEESPEVAEHNQGLVNSLINMHFEGRWLVAKEQLPLLLAQSLQLIQKL 198
            ..:|...:.|. |::..|:||                   .|.|..|
Mosquito   226 YSLATAAVNCL-RIVVTLDES-------------------GGEWTNA------------------ 252

  Fly   199 VTRQPDYAAQRVPELMGLVQCYLQYGAEGETHLKPRKLPPAQQSAAYGQEKEEEDQLLAQMSRPC 263
                      ::..|:|:.:.::.||......|.|:::|.:||.....|.        ..:|:.
Mosquito   253 ----------QLGRLIGVSKAFMMYGIPDVGKLLPQRVPVSQQGIPEPQH--------IPISKG- 298

  Fly   264 GRKNKVRKMRSLAKQ------RNQAV-NEHHEPNPRERLVLMGNQDY------------------ 303
            |:..|.||.|:..|.      ||... |...:|:..:    :..|.|
Mosquito   299 GKTAKTRKTRTHPKNKRGGGARNSGTGNREKQPSDGD----INRQPYSEASIVLEWSSKCQPPLA 359

  Fly   304 GCL-TGDSGENGLPSDSDQQQTENKHHRHQEAKVRISALHLLSTLTNQLPRRSFYGYWHVLFPDG 367
            ||. |.||..:...:.|.:.|.|    ||:.||:|.:||.|:.||...:.:|..:||||.||||.
Mosquito   360 GCYQTSDSDYSETEATSSRAQIE----RHRSAKLRQAALVLIGTLAQHVEKRIMFGYWHALFPDE 420

  Fly   368 D-AGGTPHLLLLGLKDTNFRCRALALQVGAQLLYGSKAFLSQA-CSLGP-SNFTPFAVSLASSVL 429
            . ...|..||...|:|.:.:||..|:|..:.|||.||.||.|| .|..| .:||||:|:|.:.|:
Mosquito   421 TRTPATVSLLNCVLRDPSPKCRIAAIQATSFLLYKSKPFLIQAESSKKPLVSFTPFSVTLGNMVI 485

  Fly   430 TAYRILIAILEREYTPPVLTQCLKCLAVLVQATPFHQLEMGFVYEFVGHVKKLIKSSDPPVAVSA 494
            ..|.:|...|..|....||||.||.|.|.:||||||:|.:|....||..|:.|::..||.:.|:|
Mosquito   486 EMYAMLTQALTLESDLTVLTQLLKGLTVFIQATPFHRLRVGIASRFVKIVRPLVRHRDPTIKVAA 550

  Fly   495 LLVMEMLVGTSKLTPEIASSIGL-----APSQRNLQMEHASTA-------ETYQELCDSDAEMEL 547
            |:||..|:..:.:|.|||..:|:     ||:....:.:..:.|       |.::|....|:|.|.
Mosquito   551 LMVMGFLISVADMTEEIAGLVGIKRLAKAPTGNVARSKPVAKAFDLEVNQEEHEEEEAQDSEPEE 615

  Fly   548 EEGDEQQQ---PSQNNVVNPVHTVSPTIPRNSWLLRQVLRCLEGMRIPSA---VRLECFQVLQAM 606
            ||..|.:|   |::|        ........||||:..|..|....:..:   ||:||.|||.||
Mosquito   616 EEPSEAKQDDTPNEN--------TDGGGSSMSWLLQVTLENLGVNGVACSVMPVRMECLQVLCAM 672

  Fly   607 ATHIGLLRGHQVRLSRVISAGLTDPATDVKLYAARCLDSVGYQL--GRLLPEPAEREL---QMSF 666
            ::|..||..|...:::.:.....||.:::||||.|.||.:|:.|  ..||.:..:.||   .:.|
Mosquito   673 SSHFSLLADHLPMVAQALVNAFGDPLSEIKLYAGRLLDLLGHALHTALLLEDKIDPELLDVALQF 737

  Fly   667 WLTLLPATYEAYDSAGF--SLKCALCDALSNMGAISFERLPDGQRTALLAFLSGCASDDHEETLV 729
            |.|::|...|.......  :|:...||||.|:|...:|:.|..::.||::.|:||..||  ::.|
Mosquito   738 WTTIMPTVTEQIQDVYLIATLRSVCCDALGNIGVHVYEKFPRDRQLALISLLTGCTFDD--DSAV 800

  Fly   730 RVAALRAMAVYVLHPSLRTDLGFVENAAELTLRILGDSQLLARIKAAWALGNISDALV------- 787
            ..||.|.::||:|.||||.|:.:|||..|..|||:.|..|.||||.:|:|||.:|||:
Mosquito   801 SSAAARTLSVYILFPSLRDDVCYVENTIESILRIMRDPNLTARIKTSWSLGNATDALILNQQHHL 865

  Fly   788 ----AGIPNQTERISAELLERLIQAATKSCADNDKVRANAVRALGNLLQIL---QVQPLGNGELM 845
                ..:.:.:..||.:::.|.::.|.:|..||||||:||||.:||:|.:|   |::......|.
Mosquito   866 QHESTALEDSSVMISDDMMRRTLEVALESAKDNDKVRSNAVRTIGNVLHLLRPAQLEQPAWTSLY 930

  Fly   846 QVAMSKLLDCVTLPG--NAKVKWNACYVIGNLVKHRAFFANNRLAGI----LFPTLCQLVVQHAN 904
            |.|:.:|:..||:..  |.||||||||.:||::|:...|......|.    :||.||:.||...|
Mosquito   931 QEAIERLIQNVTVSSTVNVKVKWNACYALGNMMKNETVFLPGAGGGSWERRVFPALCETVVSSPN 995

  Fly   905 FKVRTNAAGVLLQVKQREDFSAHFPLLWRSLLDALVRSNVLESFEEYNHRDALQQQLCLAIAHLL 969
            ||||.|||..|..:.:|..:.|.|...|.:||.||.:|:.|..:.||..||:||:||||::||||
Mosquito   996 FKVRINAAQALSVIGRRAHYGAFFHQTWAALLQALEQSDNLVDYNEYKRRDSLQEQLCLSLAHLL 1060

  Fly   970 LLARSSDLPMMRESLEEDRLEEVQATWRRVAFRIVPEQSDPLFTCSPLLQQRLQG 1024
            .||...|:..|...| ....:.|:..|.||..||:||:|..|.....:|.:..:|
Mosquito  1061 RLATREDVVSMATVL-LPLYDAVRGNWVRVISRILPEKSAVLLESYRVLMELRKG 1114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16989	NP_569860.3	DUF4042	335..511	CDD:463818	76/178 (43%)
		HEAT	711..>830	CDD:441023	55/129 (43%)
		HEAT repeat	712..745	CDD:293787	13/32 (41%)
		HEAT repeat	755..785	CDD:293787	15/29 (52%)
		HEAT repeat	800..829	CDD:293787	13/28 (46%)
		HEAT repeat	845..875	CDD:293787	15/31 (48%)
		HEAT repeat	889..917	CDD:293787	16/31 (52%)
		HEAT repeat	928..950	CDD:293787	8/21 (38%)
LOC1269718	XP_308367.5	None