DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13360 and CG6908

DIOPT Version :9

Sequence 1:	NP_569859.1	Gene:	CG13360 / 31025	FlyBaseID:	FBgn0025620	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_650105.1	Gene:	CG6908 / 41410	FlyBaseID:	FBgn0037936	Length:	449	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	127/459 - (27%)
Similarity:	215/459 - (46%)	Gaps:	74/459 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KLDDKQKR-----------LGHEP-PKYLNEDFFKAALEDGLRDMRVDIKKI--IFSESSGGGGE 52
            ||..:|::           :..|| |.:|::..|:..||   ||. .|:|||  ...|.:.|.||
  Fly    23 KLSKQQRQQVNDMVRETEDIAIEPIPAWLDQQKFEPILE---RDF-PDLKKIKSFRLEPTAGKGE 83

  Fly    53 NYCSKIYRAKALYRSSKRQLDEELALIVKSIA-ITPATQFLEELA---VYLREKIFYFDVLGKLE 113
            ||.:.:.||     :.:.:|::.....:..:| |.|.:...|.:|   |:.:|:..|...:.:.|
  Fly    84 NYTTLLLRA-----NFELELNDGSEQSISYMAKILPNSGNRENVASWKVFYKERNTYGQYIPEFE 143

  Fly   114 VLIGDGSK---FGAKCLYTTREPI--QTIVFDDLTQYGYKLASRQSGLNEEHCVVILKKLGKFHA 173
            .:..|..|   ||.: .|.::..:  :.||.:||.:.|::...||:||:.:|....|:||.:|||
  Fly   144 QMYKDAGKKISFGPR-YYESQIELDDELIVLEDLGKRGFRNVDRQNGLDIQHTEATLEKLAQFHA 207

  Fly   174 SSMVLAEKEPSVREHFTTGM------LDENYIRTNERFINFMTLQCRTLANVVSKWPGYEL--LA 230
            :|.|..|.:.|..|.:...:      |.|  :|.|:            |...:..:|.|:.  |.
  Fly   208 ASAVRFELKGSYPEEYNQNLCSVVDSLKE--LRENQ------------LKAYIDAFPLYDASHLT 258

  Fly   231 EKLHRHCDNIKENLVTTGRPLPGEITVLNHGDLWVNNFMYKYDDEQPTKPIDAIFVDFQNSFFGS 295
            ..:..:.....:...:....:.||..||||||.|.||.||:||  :..|..:..|||.|.|.|.|
  Fly   259 NDVQAYGSQADDMFQSFAPKIEGEFRVLNHGDAWCNNIMYQYD--EAGKLAEVNFVDLQMSRFSS 321

  Fly   296 PGCDINFFLNSSVQLDVLIHRREFLIQTYYASLRDSLERM-HSAFVPSYADIQQEIRARELYGFF 359
            |..|:.:.:.||.:||:.|.:.::||:.|:..|.:||:.: :...:||...:.|.|   .:||.:
  Fly   322 PAQDLLYLILSSTELDIKIAKFDYLIKFYHEKLIESLKLLKYPKPLPSLRSLHQSI---FIYGDW 383

  Fly   360 ---SSYAFLPMVTMKKEDSYDISIEALSDQDFAKKKVQLMFSSNPRT----TDTLRYALRRFDDL 417
               .....||:|.:...|  |.::::|.|.:.|..|::.....|.|.    .:.|.:|.||
  Fly   384 ILPIVSILLPLVLIDGGD--DANMDSLMDGEGAGDKIRNNMFKNHRVIKHQKEILPWAHRR---- 442

  Fly   418 GIFD 421
            |.|:
  Fly   443 GAFE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13360	NP_569859.1	EcKinase	50..335	CDD:281023	86/301 (29%)
CG6908	NP_650105.1	EcKinase	81..363	CDD:281023	86/303 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459213
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950