DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13360 and CG11891

DIOPT Version :9

Sequence 1:	NP_569859.1	Gene:	CG13360 / 31025	FlyBaseID:	FBgn0025620	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001027211.3	Gene:	CG11891 / 3772439	FlyBaseID:	FBgn0039309	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	131/430 - (30%)
Similarity:	211/430 - (49%)	Gaps:	50/430 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PKYLNEDFFKAAL-----EDGLRDMRVDIKKIIFSESSGGGGENYCSKIYRAKALYRSSKRQLDE 74
            |.:|..|:.:..|     .|.||.:.:|||..:      |.||||.|.|.|....|.:.|.: |:
  Fly    13 PAWLTRDYVEQKLRSYFRNDSLRLVNLDIKLAL------GNGENYSSVITRIYVEYTTDKSK-DK 70

  Fly    75 ELALIVKSIAITPATQFLEELAVYLREKIFYFDVLGKL-EVL---IGDGSKFGAKCLYTTREPIQ 135
            :.....:.....||.|.|....||.||...|..:|.:: ||:   :.|..|..|..:|..|:. .
  Fly    71 QSTRFTRFADAGPAAQVLLSYGVYNRELDLYERILPQMAEVVRNELADSRKLFAGTVYVDRKR-D 134

  Fly   136 TIVFDDLTQYGYKLASRQSGLNEEHCVVILKKLGKFHASSMVLAEKEPSV-REHFTTGMLDENYI 199
            :|:|:|::...|::|.|...|:.||..::|:||..|||:...|||::|.: .::|..|..:: :.
  Fly   135 SIIFEDMSLENYRVADRLKKLDLEHTHLVLEKLANFHAAGAALAERQPGIFAKNFDRGFFNQ-HT 198

  Fly   200 RTNERFI-NFMTLQCRTLANVVSKWPGYEL---LAEKLHRHCDNIKENLVTTGRP----LPGEIT 256
            |..|..: |.:....|:|          ||   |.::.....|.:.||::..|..    :||:..
  Fly   199 RGYEPIMKNLLMALSRSL----------ELEPDLCQRYQAKIDRLVENVMEYGERSTTIVPGDFL 253

  Fly   257 VLNHGDLWVNNFMYKYDDEQPTKPIDAIFVDFQNSFFGSPGCDINFFLNSSVQLDVLIHRREFLI 321
            .|.|||||..|.|::|||:  ..||:|||:|||.|.:.||..|:::|.::::|.|:.:.::..|:
  Fly   254 TLAHGDLWTTNIMFQYDDK--GHPINAIFIDFQFSAWNSPAIDLHYFFSTALQADIRLKKQPELV 316

  Fly   322 QTYYASLRDSLERM-HSAFVPSYADIQQEIRARELYGFFSSYAFLPMVTMKKEDSYDISIEALSD 385
            |.||..|..:|::: :|..|||.....|:.|.|..|..|:|..|.|.:|      |....||..|
  Fly   317 QFYYYKLNAALKKVQYSGNVPSLFVFHQQFRNRSFYAAFASLIFEPTMT------YTGKEEASMD 375

  Fly   386 QDFAKKKVQLMFSSN----PRTTDTLRYALRRFDDLGIFD 421
            |..:..:..:.|..:    ..|...:|..|...|.||:.|
  Fly   376 QIISLSEKGMRFKDDAFQAEETRKKMRLTLPFLDHLGLLD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13360	NP_569859.1	EcKinase	50..335	CDD:281023	94/297 (32%)
CG11891	NP_001027211.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	5	5.010