Protein Alignment tw and PMT5

DIOPT Version :9

• Sequence 1: NP_001259102.1
• Gene: tw / 31024
• FlyBaseID: FBgn0086368
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_010190.1
• Gene: PMT5 / 851464
• SGDID: S000002251
• Length: 743
• Species: Saccharomyces cerevisiae
• Alignment Length: 797
• Identity: 219/797 - (27%)
• Similarity: 357/797 - (44%)
• Gaps: 130/797 - (16%)

  Fly     4 SVVKTPKCPRRGSVKDVAQNAPRTAPTSSKEANWNWWLLLATVFLVTFATRFYKVTEPDHICWDE 68
            |.:.|..|....|::.|         |||||.     ||:..:.:.|...|.:.::.|:.:.:.|
Yeast    24 SFLITKPCDNLSSLRTV---------TSSKEK-----LLVGCLLIFTAIVRLHNISLPNSVVFGE 74

  Fly    69 THFGKMGSWYINRTFFFDVHPPLGKMLIGLSGYLTGYNGTFPFEKPGDKYN-ETRYQGMRYFCTT 132
            ...|...|.|:|..||.||||||..||......:.||.|.|.:...|.:|. ...|..||:|..|
Yeast    75 NEVGTFVSQYVNNIFFTDVHPPLVAMLYATVSSVFGYKGLFNYGNIGTEYTANVPYVAMRFFSAT 139

  Fly   133 LGALIMPMGFDTVYDLTRSHEAALLAAAYLIFDVGLLTLNQYILLDPILLFFMMASVW------- 190
            ||.:.:.:.:.|:.........|.:.|.....:...:||:::.|::...:|||..:|:
Yeast   140 LGIVSVLVLYLTLRVSGVKIAVAAICAVCFAIENSFVTLSRFTLIEGPFVFFMACAVYFFRRSEL 204

  Fly   191 ---GMVKVSKSTASGGSYGLRWWLWLFLTGTMLSCTISVKFVGLFVVLLVGLHTATELWLILGDL 252
               ...|.:||              |......|...:|.|:.|||.:...|:.....:|.::|||
Yeast   205 YLPNSCKANKS--------------LLAASIALGFAVSSKWAGLFTIAWAGIIVLWRVWFMIGDL 255

  Fly   253 GQPILETVKQLACRAITLIVWPVLLYILFFYIHLSVLNRSGNGDGFYSSAFQSRLIGNSLYNASM 317
            .:||..::|.:|.:...|:..|..:|.|.|.:|:..||.:|....|:.:.|:..|..|::...::
Yeast   256 SRPIGSSIKYMAFQFTCLLAIPAFIYFLIFSVHIKTLNVNGISSSFFPAEFRKTLKYNNVIKETV 320

  Fly   318 PRDVAYGSLVTIKNHKTGGGYLHSHHHLYPKGSGARQQQVTTYTHKDENNKWLIRPHNKPGPPKG 382
             .:||.||.|::.:..|.|||||||.|.||.||  .|||||.|.|.|:||||:|.....|.....
Yeast   321 -AEVAVGSAVSLNHVGTAGGYLHSHLHNYPAGS--MQQQVTLYPHIDQNNKWIIELAEHPNENVT 382

  Fly   383 KVQILRHGDLVRLTHMATRRNLHSHNEPAPMTKK---HLQVTGYGELGL-GDANDVWRVLI---- 439
            ..|.|..|.:::|..:.....||||:...|:::.   ..:|:.||..|. ||.||.|.:.|
Yeast   383 SFQNLTDGTIIKLRQLKNGCRLHSHDHKPPVSQNADWQKEVSCYGYEGFEGDINDDWIIEIDKKR 447

  Fly   440 -VGGKVNETVHTVTSRLKFIHLLQNCALTSSGKQLPKWGFEQQEVSCNPNVRDKNSQWNVEDNEH 503
             ..|...|.:..:.::.:..|.|..|.|.|..::||:|||.||||:|....|:..:.|.:|:||:
Yeast   448 SEPGPAQEHIRAIETKFRLKHYLTGCYLFSHPEKLPEWGFGQQEVTCAYFAREDLTSWYIEENEN 512

  Fly   504 KL-MPS---VSFSVYAPGFFARFLESHAVMLQGNAGLKPKEGEVTSRPWQWPINYRG-QFFSGSS 563
            :: :|:   ||:...:  |:.:|:..|..|...|..:..... .:|.|..||:..|| .|::.:.
Yeast   513 EISLPNPEKVSYKKMS--FWQKFVAIHKFMFYLNNYMDTSHA-YSSEPKTWPLMLRGIDFWNENG 574

  Fly   564 YRIYLLGNPLIWWSNLVFLALFVTVFLCNAVVQQRRAGFARSAAQNQAQVPDSETVAQDEESEHS 628
            ..:|.|||.::|||        ||.|:|..::     |.|......:..|    .:.:|
Yeast   575 REVYFLGNAVLWWS--------VTAFICTFII-----GVAVELLAWKLGV----NILRD------ 616

  Fly   629 TTDICSCCTPAKEIVPKAVPSGSPEAPNPAQSLRAAAWLF-LGWMLHYLPFWAMGRVLYFHHYFP 692
                       |.|:                :.....:.: ||:..||.|::.:|:.|:.:.|.|
Yeast   617 -----------KHII----------------NFHYQVFQYLLGFAAHYFPYFFVGQKLFLYDYLP 654

  Fly   693 ALIFNSLLTGVMYNYILRVLPKWIH-------HVILGLVLSILVYSFAAFSPLAY--GMSGPLAN 748
            |..|..|..|    :.|.::..:|.       ::::.:.:.:..|.|:..|||.|  |.|..|..
Yeast   655 AYYFGILAFG----HALDLISTYISNKRNNTGYIVVAIFMVVCFYFFSEHSPLIYATGWSSNLCK 715

  Fly   749 EPNSTMYNLKWLSTWEF 765
            ..       |||.:|:|
Yeast   716 RS-------KWLGSWDF 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tw	NP_001259102.1	PMT1	41..765	CDD:224839	208/758 (27%)
		PMT	44..290	CDD:280519	66/256 (26%)
		MIR	318..374	CDD:197746	31/55 (56%)
		MIR	385..440	CDD:197746	19/63 (30%)
		MIR	446..501	CDD:197746	19/54 (35%)
		PMT_4TMC	518..763	CDD:292810	56/255 (22%)
PMT5	NP_010190.1	PMT1	22..729	CDD:224839	219/797 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002698
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101353
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2235
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740