DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tw and Sdf2l1

DIOPT Version :9

Sequence 1:	NP_001259102.1	Gene:	tw / 31024	FlyBaseID:	FBgn0086368	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_001102903.1	Gene:	Sdf2l1 / 680945	RGDID:	1585844	Length:	220	Species:	Rattus norvegicus

Alignment Length:	225	Identity:	73/225 - (32%)
Similarity:	109/225 - (48%)	Gaps:	41/225 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 LYILFFYIHLSVLNRSGNGDGFYSSAFQSRLIGNSLYNASMPRDVAYGSLVTIKN--HKTGGGYL 339
            |.:|...:.|||  |||               |.|..:|.:   |..||::.:.|  |:.   .|
  Rat    11 LTLLGLLLALSV--RSG---------------GASKASAGL---VTCGSVLKLLNTHHRV---RL 52

  Fly   340 HSHHHLYPKGSGARQQQVTTYTHKDE-NNKWLIRPHNKPGPPKGKVQILRHGDLVRLTHMATRRN 403
            |||...|  |||:.||.||.....|: |:.|.||..::.|.|:|..  :|.|..|||||:.|.:|
  Rat    53 HSHDIKY--GSGSGQQSVTGVEASDDANSYWRIRGGSEGGCPRGLP--VRCGQAVRLTHVLTGKN 113

  Fly   404 LHSHNEPAPMTKKHLQVTGYGELGLGDANDVWRVLIVGGKVNETVHTVTSRLKFIHLLQNCALTS 468
            ||:|:.|:|::... :|:.:||.|.||..|:|.|...|.....     .:.::|.|:..:..|:.
  Rat   114 LHTHHFPSPLSNNQ-EVSAFGEDGEGDDLDLWTVRCSGQHWER-----EASVRFQHVGTSVFLSV 172

  Fly   469 SGKQL--PKWGFEQQEVSCNPNVRDKNSQW 496
            :|:|.  |..|  |.||...|:....|: |
  Rat   173 TGEQYGNPIRG--QHEVHGMPSANAHNT-W 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tw	NP_001259102.1	PMT1	41..765	CDD:224839	73/225 (32%)
		PMT	44..290	CDD:280519	5/12 (42%)
		MIR	318..374	CDD:197746	22/58 (38%)
		MIR	385..440	CDD:197746	23/54 (43%)
		MIR	446..501	CDD:197746	13/53 (25%)
		PMT_4TMC	518..763	CDD:292810
Sdf2l1	NP_001102903.1	PMT1	<52..>199	CDD:224839	56/159 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810