DRSC/TRiP Functional Genomics Resources

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Protein Alignment tw and SDF2

DIOPT Version :9

Sequence 1:NP_001259102.1 Gene:tw / 31024 FlyBaseID:FBgn0086368 Length:765 Species:Drosophila melanogaster
Sequence 2:XP_011523408.1 Gene:SDF2 / 6388 HGNCID:10675 Length:230 Species:Homo sapiens


Alignment Length:225 Identity:70/225 - (31%)
Similarity:100/225 - (44%) Gaps:60/225 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   307 LIGN--SLYNASMPRDVAYGSLVTIKN--HKTGGGYLHSHHHLYPKGSGARQQQVTTYTHKDENN 367
            |:|.  |...||....|..||:|.:.|  |..   .||||...|  |||:.||.||..|..|::|
Human     8 LLGGLWSAVGASSLGVVTCGSVVKLLNTRHNV---RLHSHDVRY--GSGSGQQSVTGVTSVDDSN 67

  Fly   368 K-WLIRPHN----KPGPPKGKVQILRHGDLVRLTHMATRRNLHSHNEPAPMT-----KKHL---- 418
            . |.||..:    :.|.|      ::.|..:||||:.|.||||||:..:|::     |:.|    
Human    68 SYWRIRGKSATVCERGTP------IKCGQPIRLTHVNTGRNLHSHHFTSPLSGNQRRKQRLKGFT 126

  Fly   419 ---------QVTGYGELGLGDANDVWRVLIVG------GKVNETVHTVTSRLKFIHLLQNCALTS 468
                     :|:.:||.|.||..|.|.||..|      |:|           :|.|......|:.
Human   127 EEGIKLRFKEVSAFGEEGEGDYLDDWTVLCNGPYWVRDGEV-----------RFKHSSTEVLLSV 180

  Fly   469 SGKQLPKWGFEQQEV--SCNPNVRDKNSQW 496
            :|:|..:....|:||  ...|:   :|:.|
Human   181 TGEQYGRPISGQKEVHGMAQPS---QNNYW 207

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
twNP_001259102.1 PMT1 41..765 CDD:224839 70/225 (31%)
PMT 44..290 CDD:280519
MIR 318..374 CDD:197746 24/58 (41%)
MIR 385..440 CDD:197746 25/72 (35%)
MIR 446..501 CDD:197746 11/53 (21%)
PMT_4TMC 518..763 CDD:292810
SDF2XP_011523408.1 MIR 22..72 CDD:197746 22/54 (41%)
MIR 83..157 CDD:197746 27/79 (34%)
MIR 159..208 CDD:197746 13/63 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1928
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2235
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.840

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