DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tw and sdf2

DIOPT Version :9

Sequence 1:	NP_001259102.1	Gene:	tw / 31024	FlyBaseID:	FBgn0086368	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_001016483.1	Gene:	sdf2 / 549237	XenbaseID:	XB-GENE-489307	Length:	218	Species:	Xenopus tropicalis

Alignment Length:	179	Identity:	63/179 - (35%)
Similarity:	93/179 - (51%)	Gaps:	13/179 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 VAYGSLVTIKNHKTGGGYLHSHHHLYPKGSGARQQQVTTYTHKDENNK-WLIRPHNKPGPPKGKV 384
            |..||:|.:.|.| ....||||...|  |||:.||.||..|..|:.|. |.||........:||
Frog    31 VTCGSVVKLLNIK-HSVRLHSHDVRY--GSGSGQQSVTGVTSVDDGNSYWRIRGQTSTVCERGK- 91

  Fly   385 QILRHGDLVRLTHMATRRNLHSHNEPAPMTKKHLQVTGYGELGLGDANDVWRVLIVGGKVNETVH 449
             :::.|..|||||:.|.||||||:..:|::... :|:.:|:.|.||..|.|.|| .||:..:.
Frog    92 -LIKCGQSVRLTHVNTGRNLHSHHFTSPLSGNQ-EVSAFGDDGEGDILDDWTVL-CGGEFWQR-- 151

  Fly   450 TVTSRLKFIHLLQNCALTSSGKQLPKWGFEQQEVSCNPNVRDKNSQWNV 498
              ...::|.|...:..|:.:|:|..:....|:||. ..:..::||.|.|
Frog   152 --DDEVRFRHTSTSVFLSVTGEQYGRPINGQREVH-GMSYANQNSYWKV 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tw	NP_001259102.1	PMT1	41..765	CDD:224839	63/179 (35%)
		PMT	44..290	CDD:280519
		MIR	318..374	CDD:197746	24/53 (45%)
		MIR	385..440	CDD:197746	23/54 (43%)
		MIR	446..501	CDD:197746	12/53 (23%)
		PMT_4TMC	518..763	CDD:292810
sdf2	NP_001016483.1	MIR	30..79	CDD:197746	22/50 (44%)
		MIR	39..183	CDD:280906	53/154 (34%)
		MIR	90..144	CDD:197746	25/57 (44%)
		MIR	146..199	CDD:197746	13/57 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2235
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940