DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tw and sdf2l1

DIOPT Version :9

Sequence 1:	NP_001259102.1	Gene:	tw / 31024	FlyBaseID:	FBgn0086368	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_001003730.2	Gene:	sdf2l1 / 445275	ZFINID:	ZDB-GENE-040808-46	Length:	218	Species:	Danio rerio

Alignment Length:	208	Identity:	72/208 - (34%)
Similarity:	102/208 - (49%)	Gaps:	26/208 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 SAFQSRLIGNSLYNASMPRDV--AY---GSLVTIKN--HKTGGGYLHSHHHLYPKGSGARQQQVT 358
            |.|...::...:::....|||  :|   ||||.:.|  |..   .||||...|  |||:.||.||
Zfish     9 SVFLDLILVCLVFSPCGARDVDSSYVTCGSLVKLMNTRHSV---RLHSHDVKY--GSGSGQQSVT 68

  Fly   359 TYTHKDE-NNKWLIRPHNKPGPPKGKVQILRHGDLVRLTHMATRRNLHSHNEPAPMTKKHLQVTG 422
            .....|: |:.|.||  .|||....:...:|.|..:|:|||.|.||||||:..:|:: .|.:|:.
Zfish    69 GVDSADDANSYWRIR--GKPGSICQRGAPIRCGQAIRITHMTTGRNLHSHHFSSPLS-NHQEVSA 130

  Fly   423 YGELGLGDANDVWRVLIVGGKVNETVHTVTSRLKFIHLLQNCALTSSGKQL--PKWGFEQQEVSC 485
            :||.|.||..|||.|     :.:.|.......::|.|......|:.:|:|.  |..|  |:||..
Zfish   131 FGENGEGDDLDVWNV-----QCSATYWDREDAVRFKHTGTEVFLSVTGEQYGHPIRG--QREVHG 188

  Fly   486 NPNVRDKNSQWNV 498
            .|:....| .|.|
Zfish   189 MPSPNQHN-YWKV 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tw	NP_001259102.1	PMT1	41..765	CDD:224839	72/208 (35%)
		PMT	44..290	CDD:280519
		MIR	318..374	CDD:197746	27/63 (43%)
		MIR	385..440	CDD:197746	25/54 (46%)
		MIR	446..501	CDD:197746	15/55 (27%)
		PMT_4TMC	518..763	CDD:292810
sdf2l1	NP_001003730.2	MIR	33..82	CDD:197746	22/53 (42%)
		MIR	93..148	CDD:197746	25/60 (42%)
		MIR	156..202	CDD:197746	14/48 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2235
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840