DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tw and Sdf2

DIOPT Version :9

Sequence 1:NP_001259102.1 Gene:tw / 31024 FlyBaseID:FBgn0086368 Length:765 Species:Drosophila melanogaster
Sequence 2:NP_033169.3 Gene:Sdf2 / 20316 MGIID:108019 Length:219 Species:Mus musculus


Alignment Length:207 Identity:68/207 - (32%)
Similarity:97/207 - (46%) Gaps:43/207 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   307 LIGN--SLYNASMPRDVAYGSLVTIKN--HKTGGGYLHSHHHLYPKGSGARQQQVTTYTHKDENN 367
            |:|.  |...||....|..||:|.:.|  |..   .||||...|  |||:.||.||..|..|::|
Mouse    16 LLGGLWSAVGASNMAVVTCGSVVKLLNTRHNV---RLHSHDVRY--GSGSGQQSVTGVTSVDDSN 75

  Fly   368 K-WLIRPHN----KPGPPKGKVQILRHGDLVRLTHMATRRNLHSHNEPAPMTKKHLQVTGYGELG 427
            . |.||...    :.|.|      ::.|..:||||:.|.||||||:..:|::... :|:.:||.|
Mouse    76 SYWRIRGKTATVCERGTP------IKCGQPIRLTHINTGRNLHSHHFTSPLSGNQ-EVSAFGEEG 133

  Fly   428 LGDANDVWRVLIVG------GKVNETVHTVTSRLKFIHLLQNCALTSSGKQLPKWGFEQQEV--S 484
            .||..|.|.||..|      |:|           :|.|...:..|:.:|:|..:....|:||  .
Mouse   134 EGDYLDDWTVLCNGPYWVRDGEV-----------RFKHSSTDVLLSVTGEQYGRPISGQKEVHGM 187

  Fly   485 CNPNVRDKNSQW 496
            ..|:   :|:.|
Mouse   188 AQPS---QNNYW 196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
twNP_001259102.1 PMT1 41..765 CDD:224839 68/207 (33%)
PMT 44..290 CDD:280519
MIR 318..374 CDD:197746 24/58 (41%)
MIR 385..440 CDD:197746 23/54 (43%)
MIR 446..501 CDD:197746 11/53 (21%)
PMT_4TMC 518..763 CDD:292810
Sdf2NP_033169.3 MIR 29..80 CDD:197746 22/55 (40%)
MIR 91..146 CDD:197746 25/61 (41%)
MIR 148..197 CDD:197746 13/63 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1928
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2235
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.840

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