| Sequence 1: | NP_001096859.1 | Gene: | fz3 / 31023 | FlyBaseID: | FBgn0027343 | Length: | 646 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003498.1 | Gene: | FZD7 / 8324 | HGNCID: | 4045 | Length: | 574 | Species: | Homo sapiens |
| Alignment Length: | 525 | Identity: | 140/525 - (26%) |
|---|---|---|---|
| Similarity: | 222/525 - (42%) | Gaps: | 102/525 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 133 DDEKGQIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELM 197
Fly 198 E----LWPSFLNCDGLPQPEKHELCMQIPQEVAVPGGSPSGPPTT--GSPGVEDHPQTYRFWKSG 256
Fly 257 ASP--TSDLAG-----VLCPQNFSGSPF------NPEECVPQCQ----RDAFHTSSQKKTSETLI 304
Fly 305 LGL-SAVCFVLTLFALVTFWAEPTRFGYPERPVLFLCLCYNLFSVCYLERIVFHNQA----RMHD 364
Fly 365 VELQWRLMRPGCLLTPPCLASYITTSYLSLCAASWWLIFALCFYLSSHKKWSSEALEKRSGLFHV 429
Fly 430 LAWVPPLAPPIAALLLEKVRPSELTGMCYA--------PGFVELPALVLLLLGLYFTLRASRSLL 486
Fly 487 SLQQQLQPTLAHH------RFGQIRKRFVLFSLLYFAPTTAGVVAA------------------- 526
Fly 527 LCERYADSVPSCSTPDDCLSPTPLSAWP----ALVRIFFQLVGGTLTGLWVWSRKTCESYR---N 584
Fly 585 RLGAS 589 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fz3 | NP_001096859.1 | RRM | <19..>122 | CDD:223796 | |
| RRM_1 | 22..83 | CDD:278504 | |||
| CRD_FZ | <138..224 | CDD:295308 | 27/89 (30%) | ||
| Frizzled | 291..584 | CDD:279827 | 89/337 (26%) | ||
| FZD7 | NP_003498.1 | CRD_FZ7 | 45..169 | CDD:143575 | 29/99 (29%) |
| 7tmF_FZD7 | 243..573 | CDD:320374 | 92/344 (27%) | ||
| TM helix 1 | 253..277 | CDD:320374 | 8/23 (35%) | ||
| TM helix 2 | 286..307 | CDD:320374 | 8/20 (40%) | ||
| TM helix 3 | 337..359 | CDD:320374 | 3/21 (14%) | ||
| TM helix 4 | 380..396 | CDD:320374 | 6/15 (40%) | ||
| TM helix 5 | 418..441 | CDD:320374 | 8/22 (36%) | ||
| TM helix 6 | 472..494 | CDD:320374 | 8/23 (35%) | ||
| TM helix 7 | 523..548 | CDD:320374 | 5/26 (19%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 552..557 | 2/4 (50%) | |||
| PDZ-binding | 572..574 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141184 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D167933at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.750 | |||||