| Sequence 1: | NP_001096859.1 | Gene: | fz3 / 31023 | FlyBaseID: | FBgn0027343 | Length: | 646 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036325.2 | Gene: | FZD4 / 8322 | HGNCID: | 4042 | Length: | 537 | Species: | Homo sapiens |
| Alignment Length: | 490 | Identity: | 139/490 - (28%) |
|---|---|---|---|
| Similarity: | 225/490 - (45%) | Gaps: | 81/490 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 134 DEKGQIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELME 198
Fly 199 L---WPSFLNCDGL-PQPEKHELCMQIP--QEVAVPGGSPSGPPTTGSPGVEDHPQTYRFWKSGA 257
Fly 258 SPTSDLAGVLCPQNFSGSPFNPEECVPQCQRDA-FHTSSQKKTSETLILGLSAVCFVLTLFALVT 321
Fly 322 FWAEPTRFGYPERPVLFLCLCYNLFSVCYLERIVFHNQARMHDVE-------LQWRLMRPGCLLT 379
Fly 380 PPCLASYITTSYLSLCAASWWLIFALCFYLSSHKKWSSEALEKRSGLFHVLAWVPPLAPPIAALL 444
Fly 445 LEKVRPSELTGMCYA--------PGFVELPALVLLLLGLYFTLRASRSLLSLQQQLQPT-LAHHR 500
Fly 501 FGQIRKRFVLFSLLYFAPTTAGVVAALCE-------RYADSVPSCSTPDDCLSPTPLSAWPALVR 558
Fly 559 IFFQLVGGTLTGLWVWSRKTCESYR---NRLGASG 590 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fz3 | NP_001096859.1 | RRM | <19..>122 | CDD:223796 | |
| RRM_1 | 22..83 | CDD:278504 | |||
| CRD_FZ | <138..224 | CDD:295308 | 32/91 (35%) | ||
| Frizzled | 291..584 | CDD:279827 | 85/318 (27%) | ||
| FZD4 | NP_036325.2 | CRD_FZ4 | 42..167 | CDD:143557 | 33/96 (34%) |
| 7tmF_FZD4 | 209..509 | CDD:320166 | 85/319 (27%) | ||
| TM helix 1 | 218..243 | CDD:320166 | 6/24 (25%) | ||
| TM helix 2 | 252..273 | CDD:320166 | 10/20 (50%) | ||
| TM helix 3 | 303..329 | CDD:320166 | 4/31 (13%) | ||
| TM helix 4 | 346..362 | CDD:320166 | 6/15 (40%) | ||
| TM helix 5 | 384..413 | CDD:320166 | 7/28 (25%) | ||
| TM helix 6 | 433..460 | CDD:320166 | 7/26 (27%) | ||
| TM helix 7 | 470..495 | CDD:320166 | 6/31 (19%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 499..504 | 2/4 (50%) | |||
| PDZ-binding | 535..537 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D509772at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||