| Sequence 1: | NP_001096859.1 | Gene: | fz3 / 31023 | FlyBaseID: | FBgn0027343 | Length: | 646 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_059108.1 | Gene: | FZD3 / 7976 | HGNCID: | 4041 | Length: | 666 | Species: | Homo sapiens |
| Alignment Length: | 529 | Identity: | 125/529 - (23%) |
|---|---|---|---|
| Similarity: | 207/529 - (39%) | Gaps: | 142/529 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 144 PLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELMEL----WPSFL 204
Fly 205 NCDGLPQPEKHELCMQIPQEVAVPGGSPSGPPTTGSP-GVEDHPQTYRFWKSGASPTSDLAGVLC 268
Fly 269 PQNFSGSP------FNPEECVPQCQRDAFHTSSQKKTSETLILGL-SAVCFVLTLFALVTFWAEP 326
Fly 327 TRFGYPERPVLFLCLCYNLFSVCYL------ERIV-----------------FHNQARMHDVELQ 368
Fly 369 WRLMRPGCLLTPPCLASYITTSYLSLCAASWWLIFALCFYLSSHKKWSSEALEKRSGLFHVLAWV 433
Fly 434 PPLAPPIAALLLEKVRPSELTGMCYAPGFVELPAL---------------VLLLLGLYFTLRASR 483
Fly 484 SLLSLQQQLQPTLAHHRFGQIRKRFVLFSLLYFAPTTAGV-----------------VAALCERY 531
Fly 532 ADSVP----SCSTPDDCLSPTPLSAWPALVRIFFQLVGGTLTGLWVWSRKTCESYRNRLGASGTP 592
Fly 593 TSSLMNQSK 601 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fz3 | NP_001096859.1 | RRM | <19..>122 | CDD:223796 | |
| RRM_1 | 22..83 | CDD:278504 | |||
| CRD_FZ | <138..224 | CDD:295308 | 23/83 (28%) | ||
| Frizzled | 291..584 | CDD:279827 | 83/352 (24%) | ||
| FZD3 | NP_059108.1 | CRD_FZ3 | 24..150 | CDD:143558 | 25/96 (26%) |
| 7tmF_FZD3 | 192..512 | CDD:320161 | 83/359 (23%) | ||
| TM helix 1 | 201..226 | CDD:320161 | 9/24 (38%) | ||
| TM helix 2 | 235..256 | CDD:320161 | 7/20 (35%) | ||
| TM helix 3 | 287..313 | CDD:320161 | 3/25 (12%) | ||
| TM helix 4 | 330..352 | CDD:320161 | 8/21 (38%) | ||
| TM helix 5 | 366..391 | CDD:320161 | 4/24 (17%) | ||
| TM helix 6 | 419..444 | CDD:320161 | 6/24 (25%) | ||
| TM helix 7 | 473..498 | CDD:320161 | 7/33 (21%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 502..507 | 3/4 (75%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 538..666 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141191 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D167933at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.750 | |||||