DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz3 and sfrp5

DIOPT Version :9

Sequence 1:	NP_001096859.1	Gene:	fz3 / 31023	FlyBaseID:	FBgn0027343	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001004846.1	Gene:	sfrp5 / 448129	XenbaseID:	XB-GENE-482920	Length:	315	Species:	Xenopus tropicalis

Alignment Length:	173	Identity:	46/173 - (26%)
Similarity:	65/173 - (37%)	Gaps:	57/173 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 MIAWSDADDVSIVERNEDEDDD-----------DYKSD------------------------DEK 136
            ::.||.|::........|...:           |..||                        :.|
Frog    18 LVLWSSAEEYDYYSWQSDNFQNGRFYTKQSQCIDIPSDLHLCHNVGYKKMRLPNLLDHETMPEVK 82

  Fly   137 GQIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELMEL-- 199
            .|.:..|||:...|.|..:..|||...|:|   :.||:..|:.|||.||..|   ||  :||.
Frog    83 QQASSWVPLLAKRCHRDTQLFLCSLFAPIC---LERPIYPCRSLCEVVRDSC---AP--VMESYG 139

  Fly   200 --WPSFLNCDGLPQPEKHELCMQIPQEVAVPGGSP--SGPPTT 238
              ||..|||:..|.  .::||      :.|..||.  :.||.|
Frog   140 FPWPEMLNCNKFPL--DNDLC------ITVQFGSKQVTQPPVT 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz3	NP_001096859.1	RRM	<19..>122	CDD:223796	3/14 (21%)
		RRM_1	22..83	CDD:278504
		CRD_FZ	<138..224	CDD:295308	32/89 (36%)
		Frizzled	291..584	CDD:279827
sfrp5	NP_001004846.1	CRD_SFRP5	43..169	CDD:143553	39/141 (28%)
sfrp5	NP_001004846.1	NTR_Sfrp1_like	174..299	CDD:239635	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910