DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz3 and Corin

DIOPT Version :9

Sequence 1:	NP_001096859.1	Gene:	fz3 / 31023	FlyBaseID:	FBgn0027343	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	36/163 - (22%)
Similarity:	51/163 - (31%)	Gaps:	56/163 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 DDDDYKSDDEKGQIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLC-ETVR--GE 187
            |.|.|::            |::..|.......||:...|.|... ...|..||.|| ||:|  |.
  Fly   814 DLDSYEA------------LVDVRCYELVSLFLCTLFVPKCGQS-GATVPPCKTLCTETMRRCGF 865

  Fly   188 CMENAPPELMELWPSFLNCDGLPQPEKHELCMQIPQEVAVPGGSPSGPPTTGSPGVEDHPQTYRF 252
            ..:.....|    |.:|||.........|.|:                      |:::..:..|
  Fly   866 FFDVFGLSL----PEYLNCKLFKDFPSSEDCV----------------------GLDEVREVMR- 903

  Fly   253 WKSGASPTSDLAGVLCPQNFSGSPFNPEECVPQ 285
              :...|..|  |..|.||         .|:||
  Fly   904 --AATHPKCD--GFQCDQN---------RCLPQ 923

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz3	NP_001096859.1	RRM	<19..>122	CDD:223796
		RRM_1	22..83	CDD:278504
		CRD_FZ	<138..224	CDD:295308	22/88 (25%)
		Frizzled	291..584	CDD:279827
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	25/118 (21%)
		LDLa	911..942	CDD:238060	8/24 (33%)
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931
		Tryp_SPc	1103..1343	CDD:214473
		Tryp_SPc	1104..1346	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810