DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz3 and szl

DIOPT Version :9

Sequence 1:	NP_001096859.1	Gene:	fz3 / 31023	FlyBaseID:	FBgn0027343	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_858049.1	Gene:	szl / 353294	ZFINID:	ZDB-GENE-030530-1	Length:	282	Species:	Danio rerio

Alignment Length:	211	Identity:	50/211 - (23%)
Similarity:	78/211 - (36%)	Gaps:	53/211 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 LVSNASFRSLKANC----------CVYAPPKKKRMIAWSDADDVSIVER-------NEDEDDDDY 130
            |.|...|.||.|:.          ||..||:      .|...||...|.       :...::...
Zfish     3 LFSLLLFFSLAAHTGAFDLGQTTRCVPIPPQ------MSVCQDVPYSEMRLPNLLGHGSLEEAAP 61

  Fly   131 KSDDEKGQIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPE 195
            :|||       |..|:.:||..:||..:||.:.|:|   :.|.:..|:.:|..|:..|    .|.
Zfish    62 RSDD-------LRTLLHTGCHPQARAFVCSLIAPVC---LDRFIQPCRSVCLAVKESC----SPV 112

  Fly   196 LM---ELWPSFLNCDGLPQPEKHELCMQIPQEVAVPGGSPSGPPTTGSPGVEDHPQTYRFWKSGA 257
            |.   ..||..|||:..  ||:.:....:|:.::........|.....|.|::.|.
Zfish   113 LACHGHSWPESLNCERF--PEQDDCLTPLPKHISAFSKEFPQPACQSCPSVQESPS--------- 166

  Fly   258 SPTSDLAGVLCPQNFS 273
              ...|...||..:|:
Zfish   167 --LKTLLDSLCLNDFA 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz3	NP_001096859.1	RRM	<19..>122	CDD:223796	14/55 (25%)
		RRM_1	22..83	CDD:278504	50/211 (24%)
		CRD_FZ	<138..224	CDD:295308	25/88 (28%)
		Frizzled	291..584	CDD:279827
szl	NP_858049.1	CRD_FZ	19..158	CDD:295308	37/160 (23%)
szl	NP_858049.1	NTR_Sfrp1_like	152..282	CDD:239635	8/40 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574110
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840